Buy Skilarence (dimethyl fumarate) Online

Skilarence (dimethyl fumarate) is a prescription medication used to treat moderate to severe plaque psoriasis in adults. It is an oral medication that is available in 30 mg and 120 mg tablets.

Uses

Skilarence is used to treat moderate to severe plaque psoriasis in adults. Plaque psoriasis is a chronic autoimmune disease that causes red, scaly patches of skin to form. Skilarence can help to clear these patches and improve the appearance and comfort of the skin.

Storage Conditions

Skilarence should be stored at room temperature, away from heat and moisture.

Mechanism of Action

Skilarence works by reducing inflammation. It is thought to do this by activating glutathione S-transferase (GST), an enzyme that helps to protect cells from damage. GST also helps to break down dimethyl fumarate into monomethyl fumarate, which is the active form of the drug. Monomethyl fumarate inhibits the production of inflammatory cytokines, which are proteins that play a role in the development of psoriasis.

How to Use

Skilarence is taken orally, with or without food. The starting dose is 30 mg once a day. The dose is increased gradually every week until the patient is taking the maximum dose of 240 mg three times a day.

Important Safety Information

Skilarence can cause a number of side effects, including:

• Flushing
• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
• Lymphopenia (low white blood cell count)
• Hepatotoxicity (liver damage)

Skilarence can also increase the risk of serious infections, including tuberculosis. Before starting Skilarence, your doctor will test you for tuberculosis. Skilarence can also reactivate latent tuberculosis infection.

Indications

Skilarence is indicated for the treatment of adults with moderate to severe plaque psoriasis who are candidates for systemic therapy or phototherapy.

Precautions

Skilarence should be used with caution in patients with a history of serious infections, tuberculosis, liver disease, or lymphopenia.

Skilarence should not be used in patients with a history of hypersensitivity to dimethyl fumarate or any of the other ingredients in Skilarence.

Interactions

Skilarence may interact with other medications, including:

• Methotrexate
• Cyclosporine
• Tacrolimus
• AZA (azathioprine)
• 6-MP (mercaptopurine)

Be sure to tell your doctor about all of the medications you are taking before starting Skilarence.

Contraindications

Skilarence is contraindicated in patients with a history of hypersensitivity to dimethyl fumarate or any of the other ingredients in Skilarence.

Overdose

There is no known overdose of Skilarence. However, if you take more Skilarence than prescribed, be sure to contact your doctor immediately.

Side Effects

The most common side effects of Skilarence are flushing, nausea, vomiting, diarrhea, and abdominal pain. These side effects are usually mild and go away on their own.

More serious side effects of Skilarence include lymphopenia, hepatotoxicity, and serious infections. If you experience any of these side effects, be sure to tell your doctor immediately.

Conclusion

Skilarence is an effective medication for the treatment of moderate to severe plaque psoriasis in adults. It is important to be aware of the potential side effects of Skilarence and to talk to your doctor about whether it is right for you.