Voxzogo (vosoritide) is a prescription medicine used to increase linear growth in children with achondroplasia aged 5 years and older with open growth plates. Achondroplasia is a genetic condition that causes severely short stature and disproportionate growth.
Voxzogo is a modified type C natriuretic peptide (CNP) that binds to the natriuretic peptide receptor-B (NPR-B) to promote bone growth.
Voxzogo is given as a once-daily injection under the skin. The dose is based on the patient’s body weight.
How effective is Voxzogo?
In clinical studies, Voxzogo was shown to be effective in increasing linear growth in children with achondroplasia. In one study, children treated with Voxzogo grew an average of 1.59 inches per year, compared to 0.64 inches per year in children who received a placebo.
What are the side effects of Voxzogo?
The most common side effects of Voxzogo are:
- Injection site reactions
- Vomiting
- Decreased blood pressure
- Headache
- Fatigue
- Diarrhea
- Upper respiratory tract infection
Voxzogo can also cause more serious side effects, such as:
- Allergic reactions
- Decreased liver function
- Decreased kidney function
- Increased risk of infection
Who should not take Voxzogo?
Voxzogo should not be taken by people who are allergic to vosoritide or any of the other ingredients in Voxzogo.
Important safety information
It is important to tell your doctor about all of the medications you are taking before starting Voxzogo. Voxzogo can interact with other drugs, such as certain antibiotics and anticonvulsants.
Voxzogo should be used with caution in people with liver disease or kidney disease.
Voxzogo can cause serious side effects, such as allergic reactions and decreased liver function. It is important to monitor your liver function regularly while taking Voxzogo.
If you are considering taking Voxzogo, talk to your doctor about the risks and benefits of the medication.
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