Overview: Tramadol Retard 100x 100mg, manufactured by Sandoz, is a controlled-release formulation of tramadol hydrochloride, a centrally acting analgesic. Each tablet contains 100mg of tramadol hydrochloride, designed to provide prolonged pain relief over an extended period.
Mechanism of Action: Tramadol is a synthetic opioid analgesic that acts through dual mechanisms: it binds to mu-opioid receptors and inhibits the reuptake of serotonin and norepinephrine. This dual action contributes to its analgesic effects, providing relief from moderate to severe pain.
Indications: Tramadol Retard 100mg is indicated for the management of chronic pain conditions where continuous pain relief is necessary. It is suitable for patients who require around-the-clock treatment for an extended period.
Dosage and Administration:
- The dosage of Tramadol Retard 100mg should be individualized according to the severity of pain and the patient’s response.
- Tablets are typically taken orally, with or without food, swallowed whole to maintain the controlled-release properties.
- It is important not to crush, chew, or split the tablets, as this may compromise the extended-release mechanism.
Contraindications:
- Tramadol Retard 100mg is contraindicated in patients with hypersensitivity to tramadol or any of the tablet’s excipients.
- It should not be used in cases of acute intoxication with alcohol, hypnotics, centrally acting analgesics, opioids, or psychotropic drugs.
Warnings and Precautions:
- This medication should be used cautiously in patients with respiratory depression, head injuries, increased intracranial pressure, or impaired consciousness.
- Tramadol Retard 100mg may impair cognitive and motor function; patients should avoid activities requiring mental alertness until their response to the drug is established.
Adverse Reactions: Common adverse reactions include dizziness, somnolence, headache, constipation, and nausea. These effects are generally mild to moderate and transient.
Drug Interactions:
- Tramadol Retard 100mg may interact with other central nervous system depressants, including alcohol, benzodiazepines, and other opioids, potentially increasing sedative effects.
- Concurrent use of serotonergic drugs may lead to serotonin syndrome; caution is advised.
Storage: Store at room temperature (15-30°C) in a dry place, protected from light and moisture. Keep out of reach of children.
Packaging: Tramadol Retard 100mg is available in blister packs containing 100 tablets.
Manufacturer: Produced by Sandoz, a globally recognized pharmaceutical company known for its commitment to quality and innovation in healthcare.
Reviews
There are no reviews yet.