Buy TAMOL PLUS (Paracetamol) 150ml Online

Introduction

Tamol Plus 150ml is a paracetamol-based oral suspension manufactured by Sandoz, designed to provide effective relief from pain and fever. Paracetamol, also known as acetaminophen in some regions, is one of the most widely used over-the-counter (OTC) medications globally due to its proven efficacy and safety profile when used as directed. This oral suspension formulation is particularly suitable for children and adults who have difficulty swallowing tablets, offering a convenient and palatable alternative.

Composition

Tamol Plus contains paracetamol as the active ingredient, with each 5ml of the suspension delivering 250mg of paracetamol. The suspension also includes inactive ingredients that stabilize the formulation, enhance taste, and ensure the proper delivery of the medication.

Mechanism of Action

Paracetamol works primarily by inhibiting the synthesis of prostaglandins in the brain, which are chemicals responsible for transmitting pain signals and inducing fever. Unlike non-steroidal anti-inflammatory drugs (NSAIDs), paracetamol has minimal anti-inflammatory properties, making it a preferred option for pain relief without the gastrointestinal side effects associated with NSAIDs. Its central action on the brain’s temperature-regulating center also contributes to its antipyretic (fever-reducing) effects.

Indications

Tamol Plus 150ml is indicated for the relief of mild to moderate pain and the reduction of fever. It is commonly used to treat the following conditions:

• Headaches: Including tension headaches and migraines.
• Musculoskeletal Pain: Such as muscle aches, joint pain, and back pain.
• Dental Pain: Relief from toothaches and post-dental surgery pain.
• Cold and Flu Symptoms: Including the reduction of fever and alleviation of sore throat.
• Menstrual Cramps: To ease pain associated with menstruation.
• Post-Vaccination Fever: Commonly used to manage fever following vaccinations, particularly in children.

Dosage and Administration

Adults and Children over 12 years:
The typical dose is 10-20ml (500-1000mg of paracetamol) every 4-6 hours as needed, not exceeding 80ml (4000mg) in a 24-hour period.

Children 6-12 years:
The recommended dose is 5-10ml (250-500mg of paracetamol) every 4-6 hours as needed, not exceeding 40ml (2000mg) in a 24-hour period.

Children under 6 years:
Dosage should be determined by a healthcare professional, but a typical dose is 2.5-5ml (125-250mg of paracetamol) every 4-6 hours, not exceeding 20ml (1000mg) in a 24-hour period.

Administration:
Shake the bottle well before use to ensure the suspension is evenly mixed. Use the measuring spoon or cup provided to ensure accurate dosing. Tamol Plus can be taken with or without food.

Contraindications

Tamol Plus should not be used in individuals who have a known hypersensitivity to paracetamol or any of the other ingredients in the formulation. Additionally, caution should be exercised in patients with the following conditions:

• Severe Liver Disease: Paracetamol is metabolized in the liver, and excessive use can lead to hepatotoxicity.
• Severe Kidney Impairment: Dose adjustments may be necessary in patients with significant renal dysfunction.
• Chronic Alcoholism: Regular alcohol consumption increases the risk of liver damage from paracetamol.
• G6PD Deficiency: Individuals with this condition may be at increased risk of hemolysis.

Warnings and Precautions

• Overdose Risk: Exceeding the recommended dose of paracetamol can result in serious liver damage, potentially leading to liver failure and death. In the event of an overdose, immediate medical attention is required, even if symptoms are not apparent.
• Liver Function: Patients with pre-existing liver conditions should use Tamol Plus with caution and under medical supervision. Regular monitoring of liver function tests may be necessary.
• Kidney Function: Use with caution in patients with renal impairment, and dose adjustments may be required.
• Interactions with Other Medications: Paracetamol can interact with other medications, including warfarin (a blood thinner), other pain relievers, and certain anticonvulsants. Patients should consult a healthcare provider before combining Tamol Plus with other medications.

Adverse Reactions

Tamol Plus is generally well-tolerated when used at the recommended doses. However, like all medications, it can cause side effects in some individuals. Common side effects include:

• Gastrointestinal Issues: Such as nausea, vomiting, and abdominal pain.
• Allergic Reactions: Including skin rash, itching, and hives. Severe allergic reactions (anaphylaxis) are rare but require immediate medical attention.
• Liver Toxicity: Prolonged use or overdose of paracetamol can lead to liver damage. Symptoms of liver toxicity include yellowing of the skin and eyes (jaundice), dark urine, and severe fatigue.
• Kidney Impairment: High doses or prolonged use can affect kidney function.

Drug Interactions

Paracetamol is metabolized by the liver, and its use can be influenced by other medications that affect liver enzymes. Important drug interactions include:

• Warfarin: Paracetamol may enhance the effects of warfarin, increasing the risk of bleeding. Patients on warfarin should monitor their INR levels closely.
• Alcohol: Regular consumption of alcohol increases the risk of liver damage with paracetamol use.
• Other Paracetamol-Containing Products: To avoid the risk of overdose, patients should not take multiple products containing paracetamol simultaneously.
• Anticonvulsants: Drugs such as phenytoin and carbamazepine can induce liver enzymes, potentially reducing the effectiveness of paracetamol.

Special Populations

Pregnancy:
Paracetamol is generally considered safe for use during pregnancy when taken at recommended doses. However, pregnant women should consult their healthcare provider before using Tamol Plus.

Breastfeeding:
Paracetamol is excreted in breast milk in small amounts, but it is generally considered safe for use during breastfeeding. Nursing mothers should seek medical advice before use.

Elderly:
Elderly patients may be more susceptible to the adverse effects of paracetamol, particularly liver and kidney toxicity. Dose adjustments may be necessary, and close monitoring is recommended.

Storage and Handling

Tamol Plus should be stored in a cool, dry place away from direct sunlight. Keep the bottle tightly closed when not in use. Do not store above 25°C (77°F). Keep out of reach of children.

Packaging

Tamol Plus 150ml is supplied in an amber-colored bottle with a child-resistant cap to prevent accidental ingestion by children. The bottle is accompanied by a measuring spoon or cup to ensure accurate dosing.

Conclusion

Tamol Plus 150ml (250mg/5ml) by Sandoz is a reliable and effective oral suspension for the relief of pain and fever. Its formulation, containing paracetamol as the active ingredient, is suitable for a wide range of age groups, making it a versatile option for managing common ailments. With its convenient liquid form, Tamol Plus is especially ideal for children and adults who prefer or require an alternative to tablets. As with any medication, it is important to use Tamol Plus as directed and consult a healthcare professional if there are any concerns or questions regarding its use.