Chemical name: (6R-trans)-6-(1,3-benzodioxol-5-yl)- 2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino [1′, 2′
Formula: C22H19N3O4
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid
TADARISE-20
Overview
TADARISE-20 is a pharmaceutical product manufactured by Sunrise Remedies, specifically designed for the treatment of erectile dysfunction (ED) and benign prostatic hyperplasia (BPH). Each pack contains 10 tablets, each with a dosage of 20 mg of Tadalafil, a potent active ingredient known for its effectiveness in managing these conditions.
Active Ingredient
- Tadalafil: Each tablet of TADARISE-20 contains 20 mg of Tadalafil, a selective inhibitor of phosphodiesterase type 5 (PDE5). Tadalafil enhances blood flow to the penis during sexual stimulation, leading to improved erectile function. Additionally, it helps in alleviating the symptoms of BPH by relaxing the muscles in the prostate and bladder.
Mechanism of Action
Tadalafil works by inhibiting PDE5, an enzyme that breaks down cyclic guanosine monophosphate (cGMP). Increased levels of cGMP lead to smooth muscle relaxation in the corpus cavernosum, which results in improved blood flow and a sustained erection. For BPH, Tadalafil’s action on smooth muscle relaxation reduces symptoms such as frequent urination and difficulty in starting urination.
Indications
- Erectile Dysfunction (ED): TADARISE-20 is prescribed for the treatment of ED, a condition where achieving or maintaining an erection sufficient for satisfactory sexual performance is difficult.
- Benign Prostatic Hyperplasia (BPH): It is also used to manage symptoms of BPH, including urinary urgency, frequency, and weak stream.
Dosage and Administration
- Dosage: The recommended dose for TADARISE-20 is one 20 mg tablet taken as needed, approximately 30 minutes before sexual activity. It should not be taken more than once daily.
- Administration: The tablet should be swallowed whole with a glass of water. It can be taken with or without food, but high-fat meals may delay its onset of action.
Contraindications
- Allergy: Patients with a known hypersensitivity to Tadalafil or any other component of the tablet should avoid using TADARISE-20.
- Nitrate Use: TADARISE-20 is contraindicated in individuals taking nitrates or nitrate-containing medications, as this can lead to a significant drop in blood pressure.
- Severe Liver or Kidney Impairment: Those with severe liver or kidney impairment should not use TADARISE-20 due to the risk of increased side effects.
Side Effects
Common side effects of TADARISE-20 include:
- Headache
- Flushing
- Nasal congestion
- Indigestion
- Back pain
- Muscle pain
Serious side effects, although rare, may include:
- Sudden vision loss
- Hearing loss
- Priapism (an erection lasting more than 4 hours)
- Severe allergic reactions
Patients experiencing any severe or persistent side effects should seek medical attention immediately.
Interactions
- Drug Interactions: TADARISE-20 may interact with certain medications, including alpha-blockers, antihypertensives, and other PDE5 inhibitors. Patients should inform their healthcare provider about all the medications they are taking to avoid potential interactions.
- Alcohol: Excessive alcohol consumption can increase the risk of side effects such as dizziness and headaches.
Storage
- Temperature: Store TADARISE-20 at room temperature, between 20°C to 25°C (68°F to 77°F).
- Protection: Keep the tablets in their original packaging and protect them from moisture and light.
- Disposal: Dispose of unused or expired medication properly and in accordance with local regulations.
Precautions
- Medical History: Patients should disclose their full medical history, especially regarding heart conditions, low blood pressure, and stroke, before starting treatment with TADARISE-20.
- Sexual Activity: Engage in sexual activity cautiously if you have heart problems, as sexual activity may place an extra strain on your heart.
Conclusion
TADARISE-20 (Tadalafil Tablets 20mg) by Sunrise Remedies is a reliable choice for individuals dealing with erectile dysfunction and benign prostatic hyperplasia. By adhering to prescribed dosages and considering possible side effects and interactions, patients can effectively manage their symptoms and improve their quality of life.
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