Buy SUHAGRA-25 ( Sildenafil Citrate Tablets IP 25 mg) Online

Chemical name: 1-((3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine citrate
Formula: C28H38N6O11S
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid

SUHAGRA-25

Overview

Suhagra-25 is a pharmaceutical product containing the active ingredient Sildenafil, commonly used to treat erectile dysfunction (ED) in men. Manufactured by Cipla, a reputable and globally recognized pharmaceutical company, Suhagra-25 is designed to help men achieve and maintain an erection sufficient for sexual activity. Each pack contains four pills, each with a dosage of 25 mg of Sildenafil.

Active Ingredient

Sildenafil is a potent and selective inhibitor of the enzyme phosphodiesterase type 5 (PDE5), which is responsible for regulating blood flow in the penis. By inhibiting PDE5, Sildenafil enhances the effects of nitric oxide (NO), a natural chemical the body releases during sexual arousal. This action increases blood flow to the penis, facilitating the achievement and maintenance of an erection in response to sexual stimulation.

Manufacturer

Cipla is a leading pharmaceutical company known for its high-quality and affordable medications. With a strong presence in over 80 countries, Cipla has a long-standing reputation for excellence in the pharmaceutical industry. The company’s commitment to research, development, and innovation ensures that Suhagra-25 meets the highest standards of safety and efficacy.

Indications

Suhagra-25 is primarily indicated for the treatment of erectile dysfunction (ED) in men. Erectile dysfunction is characterized by the inability to achieve or maintain an erection sufficient for satisfactory sexual performance. It is a common condition that can result from various factors, including psychological, physical, and lifestyle-related issues.

Mechanism of Action

Suhagra-25 works by enhancing the natural erectile response to sexual stimulation. The key actions include:

1. Inhibition of PDE5: By blocking PDE5, Sildenafil prevents the breakdown of cyclic guanosine monophosphate (cGMP), a molecule that relaxes smooth muscle cells and increases blood flow to the penis.
2. Increased Nitric Oxide Release: Sexual stimulation triggers the release of nitric oxide in the penile tissue. Nitric oxide activates the enzyme guanylate cyclase, leading to an increase in cGMP levels. Sildenafil amplifies this effect, promoting sustained blood flow and erection.
3. Enhanced Blood Flow: The increased cGMP levels cause the smooth muscles in the penile arteries to relax, allowing more blood to flow into the penis. This results in an erection when combined with sexual stimulation.

Dosage and Administration

Recommended Dosage: The recommended starting dose of Suhagra-25 is 25 mg, taken approximately 30 to 60 minutes before sexual activity. Based on efficacy and tolerability, the dosage may be increased to 50 mg or reduced to 25 mg. However, the maximum recommended dose is 100 mg, and the medication should not be taken more than once a day.

Administration: Suhagra-25 should be taken orally with water. It can be taken with or without food, but a high-fat meal may delay the onset of action. It is essential to follow the prescribed dosage and not exceed the recommended amount to avoid potential side effects.

Contraindications

Suhagra-25 is contraindicated in patients with the following conditions:

• Known hypersensitivity to Sildenafil or any component of the tablet.
• Concurrent use of nitrates or nitric oxide donors, as this can lead to severe hypotension.
• Severe cardiovascular disorders, such as recent myocardial infarction, stroke, or life-threatening arrhythmia.
• Severe hepatic impairment.
• Retinitis pigmentosa, a rare genetic disorder affecting the retina.

Side Effects

Like all medications, Suhagra-25 may cause side effects. Common side effects include:

• Headache: One of the most commonly reported side effects, usually mild to moderate in intensity.
• Flushing: A sensation of warmth or redness, particularly on the face and neck.
• Dyspepsia: Indigestion or stomach discomfort.
• Nasal Congestion: Blocked or runny nose.
• Dizziness: A feeling of lightheadedness or unsteadiness.

Less common but potentially serious side effects include:

• Priapism: A prolonged and painful erection lasting more than 4 hours. This is a medical emergency and requires immediate attention.
• Sudden Vision Loss: A rare condition known as non-arteritic anterior ischemic optic neuropathy (NAION), which can cause sudden vision loss in one or both eyes.
• Hearing Loss: Sudden decrease or loss of hearing, which may be accompanied by tinnitus or dizziness.

Precautions

Before taking Suhagra-25, patients should inform their healthcare provider about any medical conditions or medications they are currently taking. This is particularly important for those with:

• Cardiovascular Disease: Patients with a history of heart disease, angina, or high blood pressure should use Sildenafil with caution.
• Renal or Hepatic Impairment: Dosage adjustments may be necessary for patients with kidney or liver problems.
• Bleeding Disorders: Sildenafil can increase the risk of bleeding, particularly in patients with peptic ulcers or other bleeding conditions.
• Retinal Disorders: Caution is advised for patients with a history of eye problems.

Drug Interactions

Suhagra-25 may interact with certain medications, potentially altering their effects or increasing the risk of adverse reactions. Key interactions include:

• Nitrates: Concurrent use with nitrates or nitric oxide donors can lead to a dangerous drop in blood pressure.
• Alpha-Blockers: Co-administration with alpha-blockers used to treat high blood pressure or prostate problems can cause symptomatic hypotension.
• CYP3A4 Inhibitors: Drugs such as ketoconazole, itraconazole, and erythromycin can increase Sildenafil levels, necessitating dosage adjustments.
• Ritonavir and Saquinavir: These HIV protease inhibitors can significantly increase Sildenafil levels, requiring dose modifications.

Storage

Suhagra-25 should be stored in a cool, dry place away from direct sunlight and moisture. The medication should be kept out of reach of children and pets. Do not use Suhagra-25 beyond the expiration date printed on the packaging.

Conclusion

Suhagra-25 by Cipla is a reliable and effective treatment for erectile dysfunction, offering a convenient dosage form with a proven active ingredient, Sildenafil. Its mechanism of action, safety profile, and ease of use make it a preferred choice for men seeking to improve their sexual performance and quality of life. As with any medication, it is essential to use Suhagra-25 under the guidance of a healthcare provider to ensure optimal results and minimize the risk of side effects.