Search

In Stock

Buy Spevigo (spesolimab-sbzo) Online

DISEASE INDICATIONS: Psoriasis

MANUFACTURER: Boehringer Ingelheim

USAGE: Intravenous

MEDICINE APPROVED BY:

European Medical Agency (EMA)

Food and Drug Administration (FDA)

Spevigo (spesolimab-sbzo) is a prescription medication used to treat generalized pustular psoriasis (GPP) flares in adults. GPP is a rare autoinflammatory skin disease that can cause painful pustules (blisters) to form all over the body. Spevigo is the first FDA-approved treatment for GPP flares.

This product is currently out of stock and unavailable.

Compare

Spevigo (spesolimab-sbzo) is a first-in-class monoclonal antibody indicated for the treatment of adults with generalized pustular psoriasis (GPP) flares. GPP is a rare and potentially life-threatening autoinflammatory skin disease characterized by widespread sterile pustules, fever, and systemic inflammation.

How Spevigo Works

Spevigo works by blocking the interleukin-36 (IL-36) pathway. IL-36 is a cytokine that plays a key role in the development and progression of GPP. By blocking IL-36, Spevigo can help to reduce inflammation and improve the symptoms of GPP.

Clinical Studies

The efficacy and safety of Spevigo were evaluated in a Phase 3 clinical trial called Effisayil-1. The trial included 114 adults with GPP flares. Participants were randomized to receive either Spevigo or placebo.

The results of the trial showed that Spevigo was significantly more effective than placebo at clearing GPP flares. At 14 weeks, 93% of participants who received Spevigo had achieved complete or nearly complete clearance of their flares, compared to only 18% of participants who received placebo.

Spevigo was also well tolerated in the trial. The most common side effects were headache, fatigue, and injection site reactions.

How to Use Spevigo

Spevigo is administered as a single intravenous infusion over 90 minutes. The recommended dose is 900 mg. If GPP flare symptoms persist, an additional intravenous 900 mg dose may be administered one week after the initial dose.

Important Safety Information

Spevigo can increase the risk of serious infections, including tuberculosis. Before starting Spevigo, your doctor will test you for tuberculosis. Spevigo can also reactivate latent tuberculosis infection.

Spevigo can also increase the risk of other side effects, such as:

  • Allergic reactions
  • Inflammatory bowel disease (IBD)
  • Psoriasis worsening
  • Injection site reactions
  • Upper respiratory tract infections
  • Headache
  • Diarrhea
  • Nausea
  • Fatigue

Indications

Spevigo is indicated for the treatment of adults with GPP flares.

Precautions

Spevigo should be used with caution in patients with a history of serious infections, tuberculosis, IBD, or other autoimmune diseases.

Spevigo should not be used in patients who have a history of severe allergic reactions to Spevigo or other biologic medications.

Interactions

Spevigo may interact with other medications, including live vaccines and biologic medications. Be sure to tell your doctor about all of the medications you are taking before starting Spevigo.

Contraindications

Spevigo is contraindicated in patients with a history of severe allergic reactions to Spevigo or other biologic medications.

Overdose

There is no known overdose of Spevigo.

Side Effects

The most common side effects of Spevigo are upper respiratory tract infections, headache, diarrhea, nausea, fatigue, and injection site reactions.

More serious side effects of Spevigo include serious infections, IBD, psoriasis worsening, and allergic reactions.

If you experience any side effects while taking Spevigo, be sure to tell your doctor.

Package

450 mg/7.5 mL (60 mg/mL) x 1 single-dose vial

Reviews

There are no reviews yet.

Write a review

Your email address will not be published. Required fields are marked *

Bestsellers

Buy Olumiant (baricitinib) Online

From $1,070.33
(0 Reviews)
DISEASE INDICATIONS: Rheumatoid Arthritis MANUFACTURER: Eli Lilly Nederland B.V. USAGE: Oral MEDICINE APPROVED BY: European Medical Agency (EMA) Olumiant (baricitinib) is a prescription medication used to treat rheumatoid arthritis (RA), alopecia areata, and COVID-19. It is a Janus kinase (JAK) inhibitor, which means that it blocks the activity of JAK enzymes. JAK enzymes are involved in the signaling pathway that leads to inflammation.

Buy Skilarence (dimethyl fumarate) Online

From $93.21
(0 Reviews)
DISEASE INDICATIONS: Psoriasis MANUFACTURER: Almirall, S.A. USAGE: Oral MEDICINE APPROVED BY: European Medical Agency (EMA) Skilarence (dimethyl fumarate) is a prescription medication used to treat moderate to severe plaque psoriasis in adults. It is an oral medication that works by suppressing the immune system and reducing inflammation.

Buy Takhzyro (lanadelumab) Online

$14,055.70
(0 Reviews)
DISEASE INDICATIONS: Hereditary angioedema (HAE) MANUFACTURER: Shire Pharmaceuticals USAGE: Subcutaneous MEDICINE APPROVED BY: European Medical Agency (EMA) Food and Drug Administration (FDA) Takhzyro (lanadelumab) is a prescription medication used to prevent attacks of hereditary angioedema (HAE) in people 2 years of age and older. HAE is a rare genetic disorder that causes episodes of swelling in the face, throat, abdomen, hands, and feet. These episodes can be life-threatening.

Buy Cibinqo (abrocitinib) Online

From $1,287.82
(0 Reviews)
DISEASE INDICATIONS: Atopic Dermatitis MANUFACTURER: Pfizer Limited USAGE: Oral MEDICINE APPROVED BY: European Medical Agency (EMA) Food and Drug Administration (FDA) Pharmaceuticals and Medical Devices Agency (PMDA) Medicines & Healthcare products Regulatory Agency (MHRA) Cibinqo (abrocitinib) is a prescription medicine used to treat adults and children 12 years of age and older with moderate-to-severe atopic dermatitis (eczema) that did not respond to other treatment and is not well controlled with prescription medicines, including biologics, or when they cannot be tolerated.

Buy Adbry (tralokinumab-ldrm) Online

$1,283.00
(0 Reviews)
DISEASE INDICATIONS: Atopic Dermatitis MANUFACTURER: Leo Pharma USAGE: Subcutaneous MEDICINE APPROVED BY: Food and Drug Administration (FDA) Adbry (tralokinumab-ldrm) is a fully human monoclonal antibody that neutralizes the activity of interleukin-13 (IL-13), a cytokine that plays a key role in the pathogenesis of atopic dermatitis. Adbry is approved for the treatment of moderate-to-severe atopic dermatitis (AD) in adults and adolescents 12 years of age and older.

Buy Zoryve (roflumilast) Online

$1,026.40
(0 Reviews)
DISEASE INDICATIONS: Psoriasis MANUFACTURER: Arcutis Biotherapeutics, Inc. USAGE: Cutaneous MEDICINE APPROVED BY: Food and Drug Administration (FDA) Zoryve (roflumilast) is a topical cream used to treat plaque psoriasis in adults and children 12 years of age and older. It works by blocking an enzyme called phosphodiesterase 4 (PDE4), which plays a role in inflammation.

Buy Ilumya (tildrakizumab) Online

(0 Reviews)
DISEASE INDICATIONS: Psoriasis MANUFACTURER: Almirall, S.A. USAGE: Subcutaneous MEDICINE APPROVED BY: European Medical Agency (EMA) Food and Drug Administration (FDA) Ilumya (tildrakizumab) is a prescription medication used to treat moderate to severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy. It is a monoclonal antibody that works by blocking the p19 subunit of interleukin-23 (IL-23), a cytokine that plays a key role in the development and progression of psoriasis.

Back to Top
Product has been added to your cart