Chemical name: 1-((3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine citrate
Formula: C28H38N6O11S
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid
SILAGRA-100
Overview:
Silagra-100 is a potent medication designed to treat erectile dysfunction (ED) in men. Manufactured by Cipla Pharmaceuticals, Silagra-100 contains sildenafil citrate, the same active ingredient found in Viagra. It works by relaxing the muscles in the blood vessels, thereby increasing blood flow to the penis during sexual stimulation. This enhanced blood flow helps men achieve and maintain a firm erection suitable for sexual activity.
Composition and Active Ingredient:
Each Silagra-100 tablet contains 100mg of sildenafil citrate. Sildenafil citrate belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors, which are known for their ability to improve erectile function by increasing blood flow to the penis.
Mechanism of Action:
Silagra-100 works by inhibiting the enzyme phosphodiesterase type 5 (PDE5). By doing so, it allows the levels of cyclic guanosine monophosphate (cGMP) to increase in the erectile tissue of the penis. This augmentation of cGMP levels promotes relaxation of smooth muscles and dilation of blood vessels in the penis, facilitating increased blood flow. As a result, men with ED can achieve and sustain an erection when sexually aroused.
Indications:
Silagra-100 is primarily indicated for the treatment of erectile dysfunction (ED) in adult men. It is suitable for use by men who have difficulty achieving or maintaining erections sufficient for satisfactory sexual performance.
Dosage and Administration:
The recommended dosage of Silagra-100 is one 100mg tablet taken orally with water, approximately 30 to 60 minutes before anticipated sexual activity. The onset of action typically occurs within 30 minutes to one hour post-administration. Silagra-100 should not be taken more than once per day.
Contraindications:
Silagra-100 is contraindicated in individuals with known hypersensitivity to sildenafil citrate or any inactive ingredients present in the formulation. It should not be used concurrently with nitrate medications or nitric oxide donors due to the potential for severe hypotension.
Adverse Effects:
Common side effects associated with Silagra-100 include headache, flushing, dyspepsia, nasal congestion, dizziness, and visual disturbances (such as blurred vision or increased sensitivity to light). These side effects are usually mild to moderate in nature and transient.
Precautions:
Before initiating treatment with Silagra-100, healthcare providers should assess the cardiovascular status of patients, as sexual activity poses a risk of cardiac complications in individuals with pre-existing cardiovascular disease. Caution is advised when prescribing Silagra-100 to patients with anatomical deformation of the penis (such as angulation, cavernosal fibrosis, or Peyronie’s disease) or conditions predisposing to priapism (prolonged erection).
Storage:
Silagra-100 tablets should be stored at room temperature (15°C to 30°C) in a dry place away from direct sunlight and moisture. Keep the medication out of reach and sight of children.
Conclusion:
Silagra-100, containing sildenafil citrate 100mg, is a reliable treatment option for men suffering from erectile dysfunction. By enhancing blood flow to the penis, it enables men to achieve and maintain erections suitable for sexual activity. As with any medication, Silagra-100 should be used as prescribed by healthcare professionals, taking into account individual medical history and potential interactions with other medications.
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