Formula: C1105H1770N318O336S26
Description: PREGNYL 5000IU is a pharmaceutical product containing Human Chorionic Gonadotropin (hCG) as its active substance. Manufactured by Organon, each ampoule contains 5000 IU of hCG. Human Chorionic Gonadotropin is a hormone naturally produced by the placenta during pregnancy. In medical practice, hCG is used for various purposes related to fertility and hormone regulation.
Active Substance:
- Human Chorionic Gonadotropin (hCG): hCG is a glycoprotein hormone that mimics the action of luteinizing hormone (LH) in the body. It plays a crucial role in the development and maintenance of the corpus luteum during pregnancy, and it stimulates the production of progesterone by the corpus luteum. In males, hCG stimulates the Leydig cells in the testes to produce testosterone.
Manufacturer:
- Organon: Organon is a pharmaceutical company known for its expertise in producing hormonal medications and fertility treatments. The company adheres to strict quality standards to ensure the safety and efficacy of its products.
Uses: PREGNYL 5000IU (Human Chorionic Gonadotropin) is primarily prescribed for:
- Fertility Treatment: It is used to stimulate ovulation in women who have difficulty conceiving due to hormonal imbalances or infertility issues.
- Hypogonadism: In men, hCG is used to stimulate testosterone production in cases of hypogonadism (low testosterone levels).
- Cryptorchidism: It may be used to help descend undescended testes in young males.
Dosage and Administration: The dosage of PREGNYL 5000IU varies depending on the condition being treated and individual patient response. For ovulation induction in women, typical dosages range from 500 to 3000 IU, administered 1 to 3 times per week, as directed by a healthcare provider. The medication is usually administered by intramuscular injection.
Storage Conditions: PREGNYL 5000IU should be stored according to the manufacturer’s instructions, typically in a cool, dry place and protected from light. Proper storage helps maintain the stability and potency of the medication. Keep the ampoules out of reach of children and pets.
Mechanism of Action: Human Chorionic Gonadotropin (hCG) acts similarly to luteinizing hormone (LH), binding to LH receptors in the ovary or testes. In women, hCG induces ovulation by stimulating the release of mature eggs from the ovarian follicles. In men, it stimulates the Leydig cells in the testes to produce testosterone.
Precautions:
- PREGNYL 5000IU should be used cautiously in patients with hormone-sensitive conditions such as prostate cancer or breast cancer.
- It is important to monitor hormone levels and ovarian response during treatment to optimize effectiveness and minimize risks.
- Patients should be aware of the potential for multiple pregnancies (e.g., twins) with fertility treatments involving hCG.
Contraindications: PREGNYL 5000IU is contraindicated in individuals with hypersensitivity to hCG or any component of the formulation. It should not be used in patients with precocious puberty, active hormone-dependent tumors, or untreated androgen-dependent tumors.
Drug Interactions: There are no significant drug interactions known with PREGNYL 5000IU. However, patients should inform their healthcare provider about all medications, supplements, and herbal products they are taking before starting treatment.
Side Effects: Common side effects of PREGNYL 5000IU may include injection site reactions, headache, fatigue, breast tenderness, and mood swings. In rare cases, ovarian hyperstimulation syndrome (OHSS) or allergic reactions may occur. Patients should seek medical attention if they experience severe abdominal pain, swelling, or difficulty breathing.
Patients should consult their healthcare provider for personalized advice and information regarding PREGNYL 5000IU (Human Chorionic Gonadotropin), including its uses, dosage, and potential side effects.
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