Buy MALEGRA-DXT (Sildenafil With Duloxetine Tablets) Online

Sildenafil Citrate 100mg
Duloxetine 30mg
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid

MALEGRA-DXT

Overview: MALEGRA-DXT is a combination medication containing two active ingredients, Sildenafil Citrate and Duloxetine, formulated to treat two common male sexual disorders—erectile dysfunction (ED) and premature ejaculation (PE). Manufactured by Sunrise Remedies, a renowned pharmaceutical company known for its commitment to quality and efficacy, MALEGRA-DXT offers a dual-action approach to enhance sexual performance and prolong intimacy.

Active Ingredients:

1. Sildenafil Citrate: Known as a phosphodiesterase type 5 (PDE5) inhibitor, Sildenafil Citrate works by increasing blood flow to the penis during sexual stimulation. This helps achieve and maintain a firm erection suitable for sexual activity.
2. Duloxetine: A selective serotonin and norepinephrine reuptake inhibitor (SSNRI), Duloxetine is effective in delaying ejaculation, thus helping to improve control over ejaculation and extend the duration of sexual intercourse.

Mechanism of Action:

• Sildenafil Citrate: Upon sexual arousal, Sildenafil Citrate inhibits PDE5 enzymes, which are responsible for the degradation of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum of the penis. This results in increased levels of cGMP, leading to smooth muscle relaxation and increased blood flow, facilitating an erection.
• Duloxetine: By inhibiting the reuptake of serotonin and norepinephrine in the central nervous system, Duloxetine prolongs the action of these neurotransmitters. This delay in neurotransmitter reuptake helps in controlling ejaculation and thereby improves sexual performance.

Indications: MALEGRA-DXT is indicated for the treatment of:

• Erectile Dysfunction (ED): Inability to achieve or maintain a penile erection sufficient for satisfactory sexual performance.
• Premature Ejaculation (PE): Ejaculation that occurs sooner than desired, often leading to distress or interpersonal difficulty.

Dosage and Administration:

• The recommended dose of MALEGRA-DXT is one tablet (130 mg Sildenafil Citrate + Duloxetine) taken orally with water.
• It should be taken approximately 1-3 hours before anticipated sexual activity.
• MALEGRA-DXT can be taken with or without food, but alcohol consumption should be limited as it may decrease the efficacy of the medication.

Contraindications: MALEGRA-DXT is contraindicated in individuals with:

• Hypersensitivity to Sildenafil Citrate, Duloxetine, or any inactive ingredients present in the formulation.
• Concurrent use of nitrates or nitric oxide donors in any form (e.g., nitroglycerin) due to the risk of severe hypotension.

Warnings and Precautions:

• MALEGRA-DXT should not be used in patients with severe hepatic impairment (Child-Pugh Class C).
• Use with caution in patients with cardiovascular disease, anatomical deformation of the penis, or predisposition to priapism (prolonged erection).
• Patients should be advised to seek medical advice if an erection persists for more than 4 hours (priapism) or if sudden vision or hearing loss occurs.

Adverse Reactions: Common adverse reactions associated with MALEGRA-DXT include:

• Headache
• Flushing
• Dizziness
• Nasal congestion
• Nausea
• Insomnia
• Fatigue

Storage: Store MALEGRA-DXT at room temperature (15-30°C), away from moisture and heat. Keep out of reach of children and pets.

Conclusion: MALEGRA-DXT, manufactured by Sunrise Remedies, combines the therapeutic benefits of Sildenafil Citrate and Duloxetine to effectively manage both erectile dysfunction and premature ejaculation. With its dual-action mechanism, MALEGRA-DXT offers men a comprehensive solution to enhance sexual performance and prolong intimacy, ensuring a satisfying sexual experience.