Chemical name: 4-[(4-cyanophenyl)-(1,2,4-triazol-1-yl)methyl]benzonitrile;
Formula: C17H11N5
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid
LETROMINA 2.5mg – ALPHA PHARMA
Letrozole is a medication classified as an aromatase inhibitor. It is commonly used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. Here’s a description of Letrozole:
- Aromatase Inhibitor: Letrozole works by inhibiting the activity of the aromatase enzyme. Aromatase is responsible for converting androgens (male hormones) into estrogen (female hormones) in the body. By blocking this conversion, Letrozole reduces the overall estrogen levels in postmenopausal women.
- Breast Cancer Treatment: Letrozole is primarily prescribed for the treatment of hormone receptor-positive breast cancer, which means that the cancer cells rely on estrogen for growth. By lowering estrogen levels, Letrozole helps to slow down or inhibit the growth of hormone-sensitive breast tumors.
- Postmenopausal Women: Letrozole is specifically indicated for postmenopausal women. It is less effective in premenopausal women because their ovaries still produce estrogen independently of aromatase.
- Adjuvant and First-Line Therapy: Letrozole may be used as adjuvant therapy (additional treatment after surgery) to reduce the risk of cancer recurrence in postmenopausal women with hormone receptor-positive breast cancer. It is also used as a first-line treatment for advanced or metastatic breast cancer.
- Side Effects: Like all medications, Letrozole may cause side effects. Common side effects include hot flashes, joint pain, fatigue, and increased risk of osteoporosis due to lowered estrogen levels. Serious side effects are rare but may include bone fractures and changes in cholesterol levels.
- Duration of Treatment: The duration of Letrozole treatment can vary depending on the specific circumstances and the stage of breast cancer. Some individuals may take it for several years, especially in the adjuvant setting.
- Prescription Only: Letrozole is available by prescription only. Its use should be supervised and monitored by a healthcare professional who will assess the benefits and potential risks for each patient.
It’s crucial for individuals prescribed Letrozole to follow their healthcare provider’s instructions closely and to report any side effects or concerns during the course of treatment. Additionally, Letrozole should only be used under the guidance of a qualified healthcare professional and is not intended for self-administration without proper medical supervision.
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