Chemical name: 1-((3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine citrate
Formula: C28H38N6O11S
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid
KAMAGRA CT-100 CHEWABLE
Description: Kamagra CT-100 Chewable tablets are a pharmaceutical formulation designed for the treatment of erectile dysfunction (ED) in adult males. Each chewable tablet contains 100 mg of sildenafil citrate, the active ingredient known for its vasodilatory properties. This medication is manufactured by Ajanta Pharma, a renowned pharmaceutical company known for its quality generic medications.
Indications: Kamagra CT-100 Chewable tablets are primarily indicated for the treatment of erectile dysfunction (ED), a condition characterized by the inability to achieve or maintain a penile erection sufficient for satisfactory sexual performance. Sildenafil citrate, the active substance in Kamagra CT-100, works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), thereby enhancing the effects of nitric oxide released during sexual stimulation. This results in smooth muscle relaxation and increased blood flow into the penis, facilitating an erection.
Pharmacodynamics and Mechanism of Action: Sildenafil citrate is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5), which is responsible for the degradation of cGMP in the corpus cavernosum of the penis. During sexual stimulation, nitric oxide is released into the corpus cavernosum. Nitric oxide activates the enzyme guanylate cyclase, resulting in increased levels of cGMP, which causes smooth muscle relaxation and increased blood flow into the penis. By inhibiting PDE5, sildenafil citrate enhances the erectile response to sexual stimulation.
Dosage and Administration:
- The recommended dose of Kamagra CT-100 Chewable is one tablet (100 mg) taken orally, approximately 30 minutes to 1 hour before anticipated sexual activity.
- The tablet should be chewed thoroughly before swallowing for faster onset of action compared to conventional tablets.
- The maximum recommended dosing frequency is once daily.
Contraindications: Kamagra CT-100 Chewable tablets are contraindicated in patients with:
- Hypersensitivity to sildenafil citrate or any component of the formulation.
- Concurrent use of nitrates or nitric oxide donors in any form (e.g., nitroglycerin) due to the potential for severe hypotension.
- Serious cardiovascular diseases, including recent myocardial infarction or stroke.
- Severe hepatic impairment.
- Severe renal impairment requiring dialysis.
Warnings and Precautions:
- Cardiovascular Risks: Patients with pre-existing cardiovascular conditions should consult a healthcare provider before using Kamagra CT-100 Chewable due to the potential risk of cardiovascular events.
- Priapism: Prolonged erection (priapism) exceeding 4 hours in duration has been reported infrequently with sildenafil citrate. Patients should seek immediate medical attention if an erection persists longer than 4 hours.
- Vision Loss: Rare cases of sudden vision loss or decreased vision have been reported with the use of sildenafil citrate. Patients should discontinue use and seek immediate medical attention in the event of sudden vision loss.
- Hearing Loss: Cases of sudden hearing loss or decreased hearing have been reported with PDE5 inhibitors. Patients should discontinue use and seek medical attention if sudden hearing loss is experienced.
Adverse Effects: Common adverse effects associated with Kamagra CT-100 Chewable include:
- Headache
- Flushing
- Dyspepsia (indigestion)
- Nasal congestion
- Dizziness
- Blurred vision
Less common adverse effects may include:
- Priapism (prolonged erection)
- Hypotension (low blood pressure)
- Syncope (fainting)
- Myocardial infarction (heart attack)
- Cerebrovascular hemorrhage (bleeding in the brain)
Drug Interactions: Kamagra CT-100 Chewable may interact with other medications, including:
- Nitrates (e.g., nitroglycerin)
- Alpha-blockers (e.g., doxazosin)
- Antihypertensive medications
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
Patients should inform their healthcare provider of all medications they are currently taking to avoid potential drug interactions.
Storage: Store Kamagra CT-100 Chewable tablets at room temperature (20°C to 25°C, or 68°F to 77°F), away from moisture and light. Keep out of reach of children.
Regulatory Status: Kamagra CT-100 Chewable tablets containing sildenafil citrate are prescription medications and are regulated as per local laws and regulations governing pharmaceutical products.
Patient Counseling Information:
- Patients should take Kamagra CT-100 Chewable tablets as directed by their healthcare provider, typically 30 minutes to 1 hour before sexual activity.
- Avoid consuming grapefruit or grapefruit juice while using this medication, as it may increase sildenafil levels in the bloodstream.
- In case of any adverse effects or persistent erection lasting more than 4 hours, seek immediate medical attention.
- This medication does not protect against sexually transmitted diseases (STDs) such as HIV/AIDS. Practice safe sex methods to reduce the risk of STD transmission.
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