Chemical name: 1-(((3-(3,4-dihydro-5-methyl)-4-oxo-7-propylimidazo(5,1-f)-as-triazin-2-yl)-4-ethoxyphenyl)sulfonyl)-4-ethylpiperazine
Formula: C23H32N6O4S
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid
FILITRA PROFESSIONAL (SUBLINGUAL)
Overview:
Filitra Professional, manufactured by Fortune Health Care, is a sublingual formulation of Vardenafil designed to treat erectile dysfunction (ED) in men. Each tablet contains 20 mg of Vardenafil, a potent PDE5 inhibitor known for its efficacy in enhancing erectile function by increasing blood flow to the penis during sexual stimulation. The sublingual route of administration allows for quicker onset of action compared to traditional oral tablets, making it an effective and convenient choice for men seeking rapid relief from ED symptoms.
Mechanism of Action:
Vardenafil, the active ingredient in Filitra Professional, works by selectively inhibiting the enzyme phosphodiesterase type 5 (PDE5), which regulates the degradation of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum of the penis. Inhibition of PDE5 results in prolonged relaxation of smooth muscles and dilation of blood vessels in the penile area, facilitating increased blood flow and engorgement of the penis with blood, thereby promoting erection during sexual arousal.
Administration and Dosage:
Filitra Professional is intended for sublingual administration, where the tablet is placed under the tongue and allowed to dissolve completely without water. This method enhances the bioavailability of Vardenafil, leading to faster absorption into the bloodstream and quicker onset of action within approximately 15-30 minutes. The recommended dosage is one tablet (20 mg) as needed, ideally taken 30 minutes before anticipated sexual activity. It is advisable not to exceed the recommended dose within a 24-hour period to avoid potential adverse effects.
Indications:
Filitra Professional is primarily indicated for the treatment of erectile dysfunction (ED) in adult men, characterized by the inability to achieve or maintain a penile erection sufficient for satisfactory sexual performance. It is effective in various underlying causes of ED, including psychological factors, vascular disorders, diabetes mellitus, and prostatectomy.
Contraindications:
- Concomitant use with nitrates or nitric oxide donors
- Hypersensitivity to Vardenafil or any component of the formulation
- Severe hepatic impairment (Child-Pugh C)
- Severe renal impairment (creatinine clearance <30 mL/min)
- Concurrent use with potent CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
Adverse Effects:
Common adverse effects associated with Filitra Professional include headache, flushing, dyspepsia, nasal congestion, and dizziness. These side effects are generally mild to moderate in nature and transient. Serious adverse reactions such as prolonged erection (priapism) and sudden loss of vision or hearing require immediate medical attention.
Precautions:
- Patients with cardiovascular disease should use Filitra Professional with caution due to the potential for cardiac risk associated with sexual activity.
- Avoid consumption of alcohol and grapefruit juice while using Filitra Professional, as they may potentiate adverse effects.
- Use with caution in patients with anatomical deformation of the penis (e.g., angulation, cavernosal fibrosis) or conditions predisposing to priapism (e.g., sickle cell anemia, multiple myeloma).
Storage:
Store Filitra Professional tablets at controlled room temperature (20-25°C) in a dry place away from direct sunlight and moisture. Keep out of reach of children and pets.
Conclusion:
Filitra Professional by Fortune Health Care offers a reliable and effective treatment option for men suffering from erectile dysfunction, utilizing the benefits of sublingual Vardenafil to provide rapid onset of action and improved sexual performance. With proper administration and adherence to dosage guidelines, Filitra Professional enhances sexual satisfaction and quality of life for men experiencing ED.
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