Chemical name: (1S)-N,N-dimethyl-3-naphthalen-1-yloxy-1-phenylpropan-1-amine
Formula: C21H23NO
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid
DURATIA-90
Overview
DURATIA-90, manufactured by Fortune Health Care, is a medication specifically designed to treat premature ejaculation (PE) in men. Each tablet contains 90 mg of Dapoxetine, a selective serotonin reuptake inhibitor (SSRI) that prolongs the time taken to ejaculate and improves control over ejaculation.
Mechanism of Action
Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin’s action at the postsynaptic cleft, and delaying the ejaculatory reflex. Unlike other SSRIs used for depression, Dapoxetine is rapidly absorbed and eliminated from the body within a few hours. This property makes it suitable for on-demand use to treat premature ejaculation.
Indications
DURATIA-90 is indicated for the treatment of premature ejaculation (PE) in men aged 18 to 64 years. It is not intended for continuous daily use but is taken as needed before anticipated sexual activity.
Dosage and Administration
- Recommended Dose: The recommended dose is one 90 mg tablet taken approximately 1 to 3 hours before anticipated sexual activity.
- Maximum Dose: Do not exceed one tablet per day.
- Method of Administration: Swallow the tablet whole with a full glass of water. It can be taken with or without food.
Onset and Duration of Action
- Onset: Effects can be noticeable within 1 to 2 hours after administration.
- Duration: The effects typically last for about 2 to 4 hours, though individual response may vary.
Efficacy in Premature Ejaculation
Clinical studies have demonstrated that DURATIA-90 significantly increases the intravaginal ejaculatory latency time (IELT) and improves control over ejaculation compared to placebo.
Side Effects
Common side effects include:
- Nausea
- Headache
- Dizziness
- Diarrhea
- Insomnia
Less common but more serious side effects may include:
- Severe allergic reactions (e.g., rash, itching, swelling of the face/tongue/throat)
- Fainting
- Seizures
If any of these severe side effects occur, discontinue use and seek immediate medical attention.
Precautions and Warnings
- Allergies: Do not use if you are allergic to Dapoxetine or any other ingredients in DURATIA-90.
- Liver or Kidney Problems: Use with caution in patients with moderate to severe hepatic impairment or renal impairment. Dose adjustment may be necessary.
- Concomitant Medications: Avoid concurrent use with other SSRIs, MAO inhibitors, thioridazine, or other drugs that may increase the risk of serotonin syndrome.
- Alcohol: Limit alcohol consumption while taking DURATIA-90, as it may increase the risk of adverse effects such as dizziness, drowsiness, and fainting.
Drug Interactions
DURATIA-90 may interact with other medications, including:
- Serotonergic Drugs: Increased risk of serotonin syndrome.
- CYP3A4 Inhibitors: May increase plasma levels of Dapoxetine.
- Thioridazine: Contraindicated due to potential for serious cardiac effects.
- Nitrates: Concurrent use with nitrates is contraindicated.
Use in Specific Populations
- Pregnancy and Breastfeeding: DURATIA-90 is not indicated for use in women. It is intended for use only in men aged 18 to 64 years.
- Geriatric Use: Limited data are available in older adults. Use with caution and consider lower doses in elderly patients.
- Pediatric Use: Not indicated for use in individuals under 18 years of age.
Storage
- Temperature: Store at room temperature between 15-30°C (59-86°F).
- Moisture: Keep in a dry place and protect from light.
- Child Safety: Keep out of reach of children.
Overdose Management
In case of overdose, seek immediate medical attention. Symptoms of overdose may include severe dizziness, fainting, and seizures. Supportive and symptomatic treatment should be administered as needed.
Patient Information
Before using DURATIA-90, discuss your medical history with your healthcare provider, including any pre-existing conditions and any other medications you are taking. Follow the prescribed dosage and administration guidelines carefully to achieve optimal therapeutic outcomes.
Conclusion
DURATIA-90 by Fortune Health Care offers a reliable treatment option for men suffering from premature ejaculation. With its rapid onset and short duration of action, it provides effective control over ejaculation, enhancing sexual satisfaction and confidence. Use this medication under the guidance of a healthcare professional to ensure safe and effective treatment of premature ejaculation.
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