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Buy AVANA-50 Avanafil Tablet 50 mg Online

CHARACTERISTICS
ACTIVE HALF-LIFE 9-10 HOURS
CLASSIFICATION PDE5 INHIBITOR
DOSAGE MEN 50-200 MG/DAY
ACNE NO
WATER RETENTION NO
HBR POSSIBLE
HEPATOTOXICITY NO
AROMATIZATION NO
ACTIVE SUBSTANCE AVANAFIL
FORM 4 PILLS X 50 MG
MANUFACTURER SUNRISE REMEDIES

$13.53

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SKU:848638

Chemical name: (S)-4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide
Formula: C23H26CIN7O3
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid

AVANA-50

Introduction: AVANA-50, containing the active substance Avanafil, is a pharmaceutical product developed by Sunrise Remedies. It is primarily used for the treatment of erectile dysfunction (ED) in men. Avanafil belongs to a class of medications known as phosphodiesterase type 5 (PDE5) inhibitors, which work by increasing blood flow to the penis during sexual stimulation, thereby facilitating an erection. AVANA-50 is available in the form of tablets, with each tablet containing 50 mg of Avanafil. The product is packaged in a convenient form of 4 pills per pack.

Active Substance: The active substance in AVANA-50 is Avanafil, a potent and selective PDE5 inhibitor. Avanafil is known for its rapid onset of action and its ability to improve erectile function by enhancing the effects of nitric oxide, a natural chemical the body produces that relaxes muscles in the penis. This results in increased blood flow to the area, allowing for a firm and lasting erection.

Mechanism of Action: Avanafil works by inhibiting the PDE5 enzyme, which is responsible for the degradation of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum. By blocking PDE5, Avanafil prevents the breakdown of cGMP, allowing it to accumulate and persist longer. cGMP is essential for the relaxation of smooth muscle cells and the dilation of blood vessels in the penis. During sexual arousal, the release of nitric oxide stimulates the production of cGMP, leading to increased blood flow and an erection. Avanafil enhances this process, making it easier for men with ED to achieve and maintain an erection.

Dosage and Administration: AVANA-50 tablets are designed for oral administration. The recommended starting dose is 50 mg, taken as needed approximately 30 minutes before sexual activity. The tablet should be swallowed whole with water. The maximum recommended dosing frequency is once per day. The dosage can be adjusted based on individual response and tolerability, but it should not exceed 200 mg within a 24-hour period. It is important to note that sexual stimulation is required for Avanafil to be effective.

Pharmacokinetics: Avanafil is rapidly absorbed after oral administration, with peak plasma concentrations reached within 30 to 45 minutes. The onset of action can be as early as 15 minutes in some individuals. The half-life of Avanafil is approximately 5 hours, which means it is eliminated from the body relatively quickly. This allows for flexibility in timing sexual activity without the need for prolonged planning. Avanafil is metabolized primarily by the liver enzymes CYP3A4 and, to a lesser extent, CYP2C9. The metabolites are excreted mainly in the feces and urine.

Efficacy: Clinical studies have demonstrated the efficacy of Avanafil in improving erectile function in men with ED. Patients taking Avanafil reported significant improvements in their ability to achieve and maintain an erection sufficient for sexual intercourse. The effectiveness of Avanafil has been observed across a wide range of patient populations, including those with diabetes, hypertension, and other underlying health conditions.

Safety and Tolerability: AVANA-50 is generally well-tolerated, with a favorable safety profile. Common side effects include headache, flushing, nasal congestion, and back pain. These side effects are usually mild to moderate in severity and transient. Rare but serious side effects include sudden vision loss, hearing loss, and priapism (prolonged and painful erection). Patients experiencing any of these symptoms should seek immediate medical attention. It is important to use AVANA-50 under the supervision of a healthcare provider, particularly in patients with cardiovascular conditions or those taking other medications.

Drug Interactions: Avanafil can interact with certain medications, potentially leading to adverse effects. It should not be used concurrently with nitrates, often prescribed for chest pain, as this can cause a dangerous drop in blood pressure. Other medications that may interact with Avanafil include alpha-blockers, antihypertensives, and other PDE5 inhibitors. Patients should inform their healthcare provider of all medications they are taking to avoid potential interactions.

Contraindications: AVANA-50 is contraindicated in individuals with a known hypersensitivity to Avanafil or any of the excipients in the tablet. It should not be used in men who are advised against sexual activity due to cardiovascular risk factors. Additionally, Avanafil is not intended for use in women or individuals under 18 years of age.

Storage: AVANA-50 tablets should be stored at room temperature, away from moisture and heat. Keep the tablets in their original packaging until ready for use to protect them from light and humidity. As with all medications, keep AVANA-50 out of the reach of children and pets.

Conclusion: AVANA-50 (Avanafil 50 mg) is a reliable and effective treatment for erectile dysfunction, offering rapid onset of action and a favorable safety profile. Manufactured by Sunrise Remedies, it provides a convenient option for men seeking to improve their erectile function and enhance their sexual experience. As with any medication, it is essential to follow the prescribed dosage and consult a healthcare provider to ensure safe and appropriate use.

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