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Buy AVANA-100 Avanafil Tablet 100 mg Online

CHARACTERISTICS
ACTIVE HALF-LIFE 9-10 HOURS
CLASSIFICATION PDE5 INHIBITOR
DOSAGE MEN 50-200 MG/DAY
ACNE NO
WATER RETENTION NO
HBR POSSIBLE
HEPATOTOXICITY NO
AROMATIZATION NO
ACTIVE SUBSTANCE AVANAFIL
FORM 4 PILLS X 100 MG
MANUFACTURER SUNRISE REMEDIES

$27.68

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SKU:691438

Chemical name: (S)-4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide
Formula: C23H26CIN7O3
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid

AVANA-100

Introduction

AVANA-100 is a potent medication used primarily to treat erectile dysfunction (ED) in men. With its active ingredient, Avanafil, AVANA-100 offers a reliable and effective solution for men seeking to enhance their sexual performance and overall quality of life. Manufactured by Sunrise Remedies, a trusted name in the pharmaceutical industry, AVANA-100 ensures high standards of quality and efficacy.

Active Substance: Avanafil

Avanafil is a selective phosphodiesterase type 5 (PDE5) inhibitor. By inhibiting PDE5, Avanafil helps to relax the blood vessels in the penis, which allows increased blood flow during sexual arousal. This enhanced blood flow leads to an erection sufficient for sexual intercourse. Avanafil is known for its rapid onset of action and shorter duration of side effects compared to other PDE5 inhibitors, making it a preferred choice for many men.

Indications

AVANA-100 is indicated for the treatment of erectile dysfunction (ED) in men. Erectile dysfunction is characterized by the inability to achieve or maintain an erection sufficient for satisfactory sexual performance. AVANA-100 is designed to help men regain confidence and enjoy a fulfilling sexual life.

Dosage and Administration

Dosage:
The recommended starting dose of AVANA-100 is 100 mg, taken as needed approximately 30 minutes before sexual activity. Based on efficacy and tolerability, the dose may be increased to 200 mg or decreased to 50 mg. The maximum recommended dosing frequency is once per day.

Administration:
AVANA-100 should be taken orally with water. It can be taken with or without food. However, taking AVANA-100 with a high-fat meal may delay its onset of action. It is important to follow the prescribed dosage and not exceed the maximum recommended dose.

Mechanism of Action

Avanafil, the active ingredient in AVANA-100, works by selectively inhibiting the enzyme phosphodiesterase type 5 (PDE5) in the corpus cavernosum of the penis. During sexual stimulation, nitric oxide is released in the corpus cavernosum, which activates the enzyme guanylate cyclase. This results in increased levels of cyclic guanosine monophosphate (cGMP), leading to the relaxation of smooth muscles and increased blood flow into the penile tissues. By inhibiting PDE5, Avanafil prevents the degradation of cGMP, thereby promoting sustained erections during sexual activity.

Pharmacokinetics

Absorption:
Avanafil is rapidly absorbed after oral administration, with peak plasma concentrations achieved within 30 to 45 minutes. The bioavailability of Avanafil is not significantly affected by food intake.

Distribution:
Avanafil is widely distributed in body tissues, with a volume of distribution of approximately 21 L. It is highly bound to plasma proteins (approximately 99%).

Metabolism:
Avanafil is primarily metabolized by the liver enzyme CYP3A4, with a minor contribution from CYP2C9. The major metabolites are inactive and are excreted mainly in the feces.

Elimination:
The terminal half-life of Avanafil is approximately 5 hours. It is excreted primarily in the feces (approximately 63%) and to a lesser extent in the urine (approximately 21%).

Side Effects

Common side effects of AVANA-100 may include:

  • Headache
  • Flushing
  • Nasal congestion
  • Back pain
  • Dizziness

These side effects are usually mild to moderate in nature and tend to diminish with continued use. If any of these effects persist or worsen, it is important to contact a healthcare professional.

Serious side effects are rare but may include:

  • Sudden vision loss
  • Sudden hearing loss
  • Priapism (prolonged and painful erection)
  • Severe allergic reactions

If any of these serious side effects occur, immediate medical attention is required.

Contraindications

AVANA-100 is contraindicated in patients with:

  • Hypersensitivity to Avanafil or any of the excipients in the tablet
  • Severe cardiovascular disorders
  • Unstable angina
  • Severe liver or kidney impairment
  • Retinitis pigmentosa
  • Concurrent use of nitrates or nitric oxide donors

Drug Interactions

AVANA-100 may interact with certain medications, including:

  • Nitrates (e.g., nitroglycerin)
  • Alpha-blockers (e.g., tamsulosin)
  • Antihypertensives (e.g., amlodipine)
  • CYP3A4 inhibitors (e.g., ketoconazole)
  • Other PDE5 inhibitors (e.g., sildenafil, tadalafil)

It is essential to inform the healthcare provider of all medications and supplements being taken to avoid potential interactions.

Precautions

Before taking AVANA-100, patients should inform their healthcare provider if they have any underlying medical conditions, including:

  • Heart disease
  • High or low blood pressure
  • Liver or kidney disease
  • History of stroke or heart attack
  • Eye disorders

AVANA-100 should be used with caution in patients with anatomical deformation of the penis or conditions predisposing them to priapism.

Storage

AVANA-100 should be stored at room temperature (20-25°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children.

Conclusion

AVANA-100 is a highly effective medication for treating erectile dysfunction, offering a rapid onset of action and a favorable safety profile. Manufactured by Sunrise Remedies, AVANA-100 provides men with the confidence and ability to achieve and maintain an erection, enhancing their sexual experience and overall quality of life. With proper usage and adherence to prescribed guidelines, AVANA-100 can be a valuable addition to the management of erectile dysfunction. Always consult with a healthcare professional before starting any new medication to ensure it is appropriate for your individual health needs.

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