Chemical name: 2,2′-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]bis(2-methylpropanenitrile)
Formula: C17H19N5
Product Description
Introduction
ANTREOL-1 ANASTROZOLE Tablets IP 1mg is a highly effective medication designed to manage and treat hormone receptor-positive breast cancer in postmenopausal women. This medication belongs to the class of drugs known as aromatase inhibitors and is manufactured by Knoll Healthcare, a trusted name in pharmaceuticals.
Active Ingredient
Each tablet contains 1 mg of Anastrozole, an aromatase inhibitor that significantly reduces the amount of estrogen in the body. By lowering estrogen levels, Anastrozole helps slow or reverse the growth of estrogen-dependent breast cancer.
Indications
ANTREOL-1 is primarily indicated for:
- Postmenopausal Women: Treatment of hormone receptor-positive early breast cancer.
- Advanced Breast Cancer: First-line treatment in postmenopausal women with hormone receptor-positive or hormone receptor unknown locally advanced or metastatic breast cancer.
- Adjuvant Treatment: As an adjuvant treatment for postmenopausal women with hormone receptor-positive breast cancer to prevent recurrence.
Dosage and Administration
- Recommended Dose: One tablet (1 mg) taken orally once daily.
- Administration: The tablet should be swallowed whole with water, with or without food, at the same time each day to maintain an even level of the medication in your body.
- Duration: The duration of treatment will be determined by the healthcare provider based on the individual’s response and clinical condition.
Mechanism of Action
Anastrozole works by inhibiting the enzyme aromatase, which is responsible for converting androgens into estrogens. By blocking this conversion, Anastrozole effectively reduces estrogen levels, thereby slowing the growth of estrogen-dependent breast cancer cells.
Side Effects
Common side effects may include:
- Hot flashes
- Joint pain or stiffness
- Weakness
- Sore throat
- High blood pressure
- Nausea and vomiting
- Rash
Serious side effects may include:
- Osteoporosis or bone fractures
- Liver function changes
- Severe allergic reactions
Patients experiencing severe side effects should seek immediate medical attention.
Precautions and Warnings
- Pregnancy and Breastfeeding: Anastrozole is contraindicated in pregnant women and should not be used by women who are breastfeeding.
- Liver and Kidney Function: Caution is advised for patients with liver or kidney impairment.
- Bone Health: Regular monitoring of bone density is recommended as Anastrozole may cause bone thinning.
- Drug Interactions: Patients should inform their healthcare provider of all medications they are taking, as Anastrozole can interact with certain drugs.
Storage
- Store in a cool, dry place away from direct sunlight.
- Keep out of reach of children.
- Do not use after the expiration date indicated on the packaging.
Manufacturer Information
Knoll Healthcare
Renowned for its commitment to quality and innovation, Knoll Healthcare is a leading pharmaceutical manufacturer dedicated to providing effective and reliable medications. Their rigorous quality control processes ensure that every product meets the highest standards of safety and efficacy.
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