How tall will the child grow in the future?

If you are not tall, are you destined to only get “genetic height”, or can you turn things around through intervention?

Can a bone age test provide early access to a medical protocol that can help the child’s height?

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I’m sure every parent has a long list of questions about their child’s height.
Xiao Mei recommends this height collection for everyone.
Because of her small size, the author pays special attention to the height of her two children. Recently, she interviewed a specialist in short stature at the First Zhejiang Hospital.
The questions about height, including whether to use genotropin growth hormone to boost a child’s height, are well understood through 14 questions that parents care about most.

Because it’s so useful, I have to share it with you. The message from this article is clear: if your baby is undersized and showing signs of early development before the age of 10, take him to a professional doctor as soon as possible, and intervene as soon as possible.

The article is relatively long, and the dry academic content has been bypassed. It is practical and easy to understand. First, give the key points, and then we will read slowly:

1. Babies tend to be short before they develop, so is it difficult for them to leap up the day after tomorrow?

2 parents are not tall, baby is shorter than the same age, can play growth hormone?

3. The child’s height development is normal, but the parents of the child’s height expectation is relatively high, can you play?
4. At what age is it safer to get involved?
   Is there a big difference between early intervention and late intervention?
5. What kinds of growth hormones are available in the market and how much do they cost?

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The heat has been very high “youth with you 2” finally ended last week, in addition to the full screen of long legs envy, for the photo in The height of CAI Xukun is also let me very sigh, standing in the first row, and the second row of girls shoulder to shoulder, grow tall really have advantages ah ↓

Look at the face of the society, the appearance of the image, height is really in the employment, the choice of a spouse in the direct impact.

The height of 182 of the world elder sister Zhang Zi Lin, 3 years old daughter height has reached the waist of the mother, height advantage breakthrough sky

The long legs of lu Yi’s family are so good that they are in a coma

People Shared on Zhihu: 1.9m tall, interview a professional question was not asked, easily into the central enterprise ↓

Some netizens said his experience: because the height condition is good, in the unit all the more attention, exercise opportunities, the growth rate is fast ↓

And having been a Hobbit for forty years, I am particularly struck by the question of stature.
Because of occupation, height has a great influence on career development.
When I just entered this industry, there were so many opportunities and platforms. If I could grow another 10 cm, I believe now I am far more than a news producer and announcer.

Female anchors took photos, a group of 170-height goddess in order to take care of me, can only such a body to take photos ↓

Nature is not good, the day after tomorrow to make up, for the two children’s genetic height, I have been very worried.
My brother later predicted 172, and when they grow up, it’s hard to say whether they will be in the same situation as Me.
I’ve been debating whether to give him growth hormone or not

Want to use medical intervention, with the topic of growth hormone, in our group attention has been very high, from time to time will be discussed by everyone, not tall old mother in order to the child’s genetic height simply worried heart, ↓

Like many parents, we have been “loving and worried” about growth hormones.
Faced with two completely different voices, do you have as many question marks as I do?

Last week, I had an exclusive interview with Wang Chunlin, an expert in pediatric dwarfism and endocrinology and chief pediatrician in Zhejiang I Hospital.

Chun-lin wang

Doctor of Medicine, chief physician, postgraduate supervisor, director of pediatrics, the first Affiliated Hospital of Zhejiang University School of Medicine, director of neonatology, graduated from Zhejiang University.
He has been engaged in clinical, scientific research and teaching of pediatric internal medicine diseases for more than 20 years, mainly engaged in genetic and clinical research of endocrine diseases such as short stature, growth hormone deficiency, obesity, etc.

On the same day of the interview, Director Wang Chunlin happened to be a guest on the live program of “Chinese Children’s Growth, Development and Health Communication Action” hosted by People’s Daily, answering parents’ questions about their children’s height and development.
After watching the whole live broadcast in person, I consulted Director Wang exclusively on some issues of special concern to parents in the circle of mothers.

A word of caution: today’s tweets are a bit long, but they’re practical, easy to read and full of good stuff!
In an effort to steer clear of dry academic content, Riyo compiled the article to address parents’ primary concerns.
Director Wang answered the following questions in detail:

1 parents are not tall, baby is shorter than the same age, can play growth hormone?

2 baby height development is normal, but parents to child height expectation is higher, whether can you fight?

3 How many years old intervene to compare insurance?
Is there a big difference between early intervention and late intervention?

4. Which growth hormone can be selected in the market at present, and how much is the cost?

Does taking growth hormone increase the risk of fracture in adulthood?

7. How to balance the risks and benefits brought by drugs?

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Growth hormone – “effects” and “risks.

Growth hormone as a cure for short stature and other problems, its magic “special effect”, and behind the “risk” has been the root cause of parents struggle.

Lionel Messi, the famous Argentine star, is a typical beneficiary.
He started taking growth hormone injections at the age of 12 and grew from 1.4 to about 1.7.

He said his parents gave him the injection at first, but after he learned to do it himself, he always gave it to himself.
He said with a smile that the injection was similar to a pen stick, with a small needle and no pain.

The pen-like syringe is common in China and is commonly used to inject insulin and growth hormone.

Others said they had grown 19cm from 147 to 166 after being injected with growth hormone, the most money their parents had ever spent.

But not everyone who gets growth hormone can achieve such ideal effect, some children, after using the drug, only grew 3cm long

The boy is 15 years old. His father is 180cm and his mother is 165cm. However, the 15-year-old is only 160cm.

Bone age tablets showed that the epiphyseal line of Xiao Wu was now semi-closed, and even with growth hormone treatment, her height would not increase more than 5cm at most.
The parents wanted to make a final effort: “Try doctor, how much taller you can be, is better than nothing!”

In this way, after half a year of medication, Xiao Wu’s height only increased by 3cm. The bone age film taken last month showed that the bone scale line had been completely closed, and the lifetime height was fixed at 163cm.

Not that the effect varies from person to person is the key, parents are the biggest worry, tall, but with other adverse reactions to trade ↓

In the face of two completely different voices, how should parents scientifically understand growth hormone and make the judgment that suits their baby?
The following part of director Wang Chunlin’s exclusive interview may help you.

Increased growth hormone, suitable for your family?

1. What evaluations does the doctor perform?
   What is the basis for intervention and medication?

There are so many things to assess, bone age, annual growth rate, pituitary space-occupying lesion, blood routine, blood sugar, liver and kidney function, thyroid function, drug stimulation…
All need comprehensive evaluation!

Growth hormone drugs to stimulate, in particular, is made of the need to be hospitalized, it will be altogether five times, see the highest in the secretion of growth hormone (because of the growth hormone secretion, a pulse type high will be low, the secretion of day is lower, normal is not to come out of, only after excitation with medicine, can see that it maximum secretion).

If the peak is more than 10, the child’s growth hormone secretion is normal;
A peak of less than 10 indicates a deficiency of growth hormone, which requires intervention and supplementation.

2. Is it true that it doesn’t matter if you’re shorter when you’re a child, you’ll pop up when you hit puberty?

Unfortunately, if a child is consistently short until he or she develops, the ‘leap up’ becomes more difficult.

But there are exceptions.
For example, Director Wang told me, small when short, but later development late, to high school, even the university is still growing, this kind of situation belongs to the delay of physical puberty in medicine.

The most obvious characteristic is shorter than their peers, but not particularly short, just caught in the lowest standard, reached the level of p3, such children often his development has always been along the p3 in this line, at the same time every year a 5 cm long, keep in the growth rate of the lower limit (the standard rate in 5 ~ 7 cm/year), their age of puberty, he didn’t also development, it belongs to the later development.

I intercepted this director Wang said P3 line, everyone reference ↓

In addition, director Wang also mentioned late development is a very important basis — family genetics, namely parents, brothers and sisters, maternal grandparents, maternal grandparents…
There are not many people of late development in lineal lineages.

If more, that child late development rate is still relatively high, which means later growth;
But if there are no late bloomers in the family, and the parents themselves are short, it may be too optimistic to hope for a higher puberty.

3. Do children with late development need to be injected with growth hormone?

This depends on his “late” to what level, it is recommended that parents take their children to the hospital as soon as possible diagnosis.

Many children are considered by their parents to be late in development from an early age and do not intervene until they reach their ideal height at puberty.

Wang, give me an example: 10 ~ 11 year old boy, only 1 meter height 35, after the development in the role of sex hormones, the original backward bone age 1, 2 years, now just six months will take to speed up the epiphyseal closure, it needs to develop after only 25 to 30 cm long, add up to an optimistic situation is only 1 meter 65, parents must accept.

At this time, intervention is late intervention, and the only treatment option is:

1. Inhibit gonadal development with drugs;
2. Combined with recombinant human growth hormone therapy to improve the growth rate of children.

When both drugs are used at the same time, the child’s suffering and the cost to the parent is far greater than the early intervention.

With early intervention, the situation would be completely different: the child’s height and growth hormone would be the same as that of his peers after three to five years of treatment in the early stage of development, and then the comparison would be made. If the puberty reached the normal level of development, the parents would not have to worry later.
Therefore, parents should follow the principle of early detection, early diagnosis and early intervention for this part of the children, and should not blindly wait and miss the best intervention opportunity for height.

4, why parents are normal height, but the child is short?

There are many factors contributing to this, such as genetics.
A child born to a normal height parent with an invisible genetic condition has a one-in-four chance of developing the condition, which can make the child shorter.

Another condition is early development.
In particular, one of the parents is normal height, the other is short, the child’s early height has been at the level of P3 ~ P5, such children must pay attention to, once the emergence of early development, that is undoubtedly a further insult, because the entire adolescence also grow 20 cm (girl), the foundation is not enough, lifetime height will not be very ideal.

Developmental characteristics of boys’ secondary sexual characteristics

Girls secondary sexual characteristics development characteristics ↓

Here, Director Wang told me more regrettably: early short stature + premature, the cost is very large, finally can only as the above mentioned case, the use of inhibitory development + injection of growth hormone treatment.

5. What is the effect of intervention for children with early development?

Director Wang Shared with me a case in which he was particularly impressed:

Is a little girl, the mother only 1.5 meters, the father 1.63 meters, she was short, and 7 years old on the development, genetic height is only 1.5 meters.
After 3 years of treatment, the final height of 1.6 meters, should say or very ideal.

6, a healthy, normal height child, but the parents have a higher expectation of his height, in such a case can inject growth hormone?

If the child is doing well, there is no need to intervene.

What parents should do more is to establish a healthy lifestyle for their child, develop good habits in nutrition, exercise, sleep and so on, and then see what happens in adolescence.
There is no need to be overly anxious if the child is doing well in adolescence.

Zhang Liang son every day, Tian Liang daughter sen Dish bubble in the stadium since childhood big, big long leg no problem

7. The mother is 1.58 meters and the father is 1.70 meters. The child has inherited the height of 1.70 meters.
   Can growth hormone be used to intervene?

If the parents have a strong desire to intervene and the child has not reached the genetic height or expected height by the end of adolescence, a bone age can be taken to see how much he can expect to grow. If the situation is not ideal, a final rush with growth hormone is also clinically possible.
It is recommended that parents take their children to regular hospitals for examination before medical intervention.

70 percent of a child’s height is inherited from his or her parents

8. Are there any signs of late adolescence?
   How can parents tell if a child is in late adolescence?

The main feature is a slowdown in growth rate.
For example, before 1 cm long, now 3 months only grow less than 2 cm, that means that the growth period of the child is almost over, this time must grasp the final treatment opportunity.

Must not wait until a bit is no longer long, bone age piece discovers epiphyseal line already closed, that has no way.
So adolescent height management is very important, parents must be timely attention.

Suggest parents stick a height ruler on the wall at home, pay close attention to the child’s height

9. Does it mean that if the parents are willing to intervene, the children can be injected with growth hormone in late adolescence?

Whether or not to use growth hormone injection therapy, is based on the child’s current height, genetic height, changes in the child’s growth rate, bone age, and so on to determine the overall.

For example: boys genetic height of 1.72 meters, late puberty 1.66 meters, this height in the population is normal, but has not reached the genetic height, then this part of the children and parents if the height requirement is high or can consider drug treatment.

10. Some netizens (female, now an adult) Shared their experiences with ghrelin in adolescence and broken bones in adulthood, suggesting a connection between the two.
    Is it reasonable to worry that “playing growth hormone will cause fracture”?

Wang said there are many causes of fractures.
Growth hormone therapy can affect bone metabolism, and there is no evidence that childhood growth hormone therapy leads to an increased incidence of fracture in adulthood.

In addition, he also said: outdoor exercise in adolescence is also very important, the amount of exercise has a great impact on bone metabolism, this is the peak of metabolism, a more typical situation is the growth pain of a child growing fast, indicating that his metabolic demand is increasing, it is appropriate to supplement vitamin D.

11. What growth hormones are available on the market?
    What are their characteristics?

There are three main types: long-acting growth hormone (through independent research and development in China, the world’s first pegylated long-acting growth hormone has been born, which was developed by Jinsei Pharmaceutical And marketed in 2014), short-acting growth hormone powder and short-acting growth hormone injection.

Long-acting growth hormone: only one injection per week, the least of all the growth hormone injections, once a week, only 52 injections per year, so that the children no longer need daily injections, greatly improving the medication compliance of short stature children.
Long-acting growth hormone is much less painful to administer than short-acting growth hormone, which requires 365 days of injections, and is more medically preferable to short-acting growth hormone.
But long-acting growth hormone treatment is also more expensive for shorter duration.

Short-acting growth hormone should be injected daily. There are two main types:

One is short-acting powder.

In 1998, the first growth hormone powder in China was introduced, and the expression technology of Escherichia coli secretion was adopted.
However, due to the limitations of technology at that time, the stability of growth hormone could only be maintained through the freeze-drying process.
The freeze-drying process destroys the original spatial structure of growth hormone and increases the content of relevant substances.
In the course of the use of powder, the process of redissolution also makes the content of relevant substances increase, easy to produce antibodies, long-term efficacy reduced;
In addition, in the process of using the powder, the operation is also very complicated, requiring daily injection, which results in poor patient medication compliance and reduced long-term efficacy. However, the price of the powder is relatively the cheapest.

The other is short-acting injection, the first growth hormone injection in Asia was listed in 2005 (Changchun Jinsai Pharmaceutical Co., LTD.).
Using the protein liquid stabilization technique, which does not require freeze drying and redissolution, the growth hormone water agent can be completely consistent with the natural growth hormone.
Water agent activity is higher, will not produce antibody, can guarantee curative effect.

It is easy to operate and easy to use by using the matching hidden needle electronic pen, which is suitable for long-term use by children.

Electronic operation, accurate dose, stable injection, adjustable speed, can reduce the injection pain;
The design of hidden needle structure can’t see the needle during the whole injection process, eliminate the fear of injection and increase the compliance of patients;
Electronic operation, easy to use, suitable for long-term use of children.

It’s easy for parents to coax their kids into thinking it’s a daily energy bar.
Wang says one of his patients is a 7-year-old who can play after a month of study. That’s the convenience of the syringe pen.

In order of efficacy, long-term effect is better because of better compliance and shorter effect.

12. How should parents choose the three growth hormones?
    Is there much of a difference in cost?

Long-acting growth hormone, which is injected only once a week, significantly reduces the pain of daily injections compared to short-acting growth hormone, which is injected 365 days a week, and greatly improves medication compliance.
Therefore, Wang said that long-acting growth hormone treatment is more effective than short-acting treatment.

Short-acting water agent with hidden needle electronic pen, water agent to maintain the natural structure of growth hormone, will not produce antibodies, and added antibacterial agent, to ensure long-term injection safety.
Hidden needle structure design, to eliminate the fear of children injection, electronic intelligent design to ensure long-term safe and convenient operation of patients.

Short-acting powder changed the original spatial structure of growth hormone, and was easy to produce antibodies.
In addition, during the use of powder, the operation is also very complicated, requiring daily injection, which results in poor medication compliance of patients and reduced long-term efficacy.

Therefore, in terms of medication compliance, long-acting growth hormone > short-acting water agent > short-acting powder is the cheapest, short-acting water agent is slightly more expensive than powder, and long-acting water agent is more expensive than the other two dosage forms.

Where can I buy growth hormone on the market now?
If the child is treated in a public hospital, are all three growth hormones available?

Growth hormone is peptide medicaments, drugstore cannot sell, the outpatient department that has qualification only hospital and medical establishment has, and need to issue doctor’s diagnose a book, state case, dosage, prescription to wait clearly.

14. There are already parents in liyou’s mother circle giving their children growth hormone treatment. What should these parents pay special attention to?
15. Timely treatment and medication.

2, nutrition, diet, exercise, sleep and other factors conducive to the growth of children have to keep up.

3. Compliance, which is also what Director Wang expressed his greatest concern.
   Some parents stop and stop, which is very bad.
4. Timely review and evaluation should be conducted in accordance with the doctor’s requirements during the treatment. The nodes are the first month, the third month and every three months thereafter.

Why should you check in time?
The main thing is to look at the efficacy and safety of the drug.
Once there is any problem midway through treatment, you can intervene in time.

I hope the next generation has a pair of proud long legs, tall, handsome, beautiful, this is a very good vision, we all heartbeat and entanglement I understand, in the final analysis I am just an ordinary mother.

As parents, how to rationally and dialectically choose and choose, to reduce the risk to the minimum?
This is something we have to think about and confront.

The growth and development of children must be more scientific learning and judgment, less self-cognition, after all, the growth and development of children only a few years, once missed the best treatment opportunity, we will regret for the rest of our lives.
I hope everyone can get what they need. I really hope our children can grow up healthy and tall.