Composition: Each tablet of Sildaforce 100 contains 100 mg of Sildenafil Citrate, a potent vasodilator that belongs to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. Sildenafil Citrate helps in treating erectile dysfunction (ED) by enhancing blood flow to the penis during sexual stimulation. This mechanism allows for improved erectile function and enables the user to achieve and maintain a satisfactory erection.
Mechanism of Action: Sildenafil Citrate works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which regulates the blood flow in the penis. During sexual stimulation, nitric oxide is released into the erectile tissue of the penis. Nitric oxide activates guanylate cyclase, an enzyme that increases levels of cyclic guanosine monophosphate (cGMP). Elevated levels of cGMP lead to smooth muscle relaxation in the corpus cavernosum, allowing increased blood flow and thereby facilitating an erection.
Indications: Sildaforce 100 is indicated for the treatment of erectile dysfunction (ED) in adult males. It is effective in cases where there is a failure to achieve or maintain a penile erection sufficient for satisfactory sexual performance.
Dosage and Administration:
- The recommended dose of Sildaforce 100 is one tablet (100 mg of Sildenafil Citrate) taken orally, approximately 30 minutes to 1 hour before sexual activity.
- The tablet should be swallowed whole with a full glass of water.
- Sildaforce 100 can be taken with or without food, although taking it with a high-fat meal may delay the onset of action.
- Avoid exceeding the recommended dosage of one tablet per day to minimize the risk of adverse effects.
Contraindications: Sildaforce 100 is contraindicated in individuals with:
- Hypersensitivity to Sildenafil Citrate or any component of the formulation.
- Concurrent use of nitrates or nitric oxide donors in any form (e.g., nitroglycerin, isosorbide mononitrate, nitroprusside).
- Severe hepatic impairment (Child-Pugh Class C).
- Severe renal impairment (creatinine clearance <30 mL/min).
Warnings and Precautions:
- Use with caution in patients with anatomical deformation of the penis (e.g., angulation, cavernosal fibrosis, Peyronie’s disease) or predisposition to priapism (prolonged erection).
- Sildaforce 100 should not be used in women or children under 18 years of age.
- Patients with cardiovascular disease should consult a healthcare provider before initiating treatment with Sildaforce 100 due to the potential risk of cardiac complications.
- Alcohol consumption should be limited while taking Sildaforce 100 as it may potentiate the hypotensive effects of Sildenafil Citrate.
Adverse Reactions: Common adverse reactions associated with Sildaforce 100 include headache, flushing, dyspepsia, nasal congestion, and dizziness. These side effects are usually mild to moderate in nature and transient.
Storage: Store Sildaforce 100 tablets at room temperature (25°C) in a dry place away from direct sunlight and moisture. Keep out of reach of children and pets.
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