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Buy Tilidin 50x 200/16mg Online

Product: Tilidin 50x 200/16mg

Active substance: Tilidine

Manufacturer / Brand: Hexal AG

From $66.62

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SKU:257389

Description

Tilidin 50x 200/16mg is a potent analgesic medication primarily used for the management of moderate to severe pain. Manufactured by Hexal AG, a reputable pharmaceutical company known for its high-quality medical products, this medication combines two active substances: Tilidine and Naloxone.

Active Substances

  1. Tilidine (200 mg):
    Tilidine is a synthetic opioid analgesic that works by altering the perception of pain in the central nervous system. It is effective in reducing discomfort and improving the quality of life for individuals suffering from various types of pain, including chronic pain conditions and post-operative pain.
  2. Naloxone (16 mg):
    Naloxone is an opioid antagonist included in the formulation to counteract the potential misuse and abuse of Tilidine. It does this by blocking the effects of opioids on the brain, thus reducing the likelihood of addiction and overdose. In therapeutic doses, Naloxone does not interfere with the pain-relieving effects of Tilidine.

Indications

Tilidin 50x 200/16mg is indicated for:

  • Management of moderate to severe pain that requires opioid analgesics.
  • Treatment of chronic pain conditions that are not adequately managed by non-opioid analgesics.

Mechanism of Action

Tilidine, after oral administration, is metabolized in the liver to its active metabolite, Nortilidine, which binds to opioid receptors in the brain and spinal cord. This binding leads to a decrease in the perception of pain and an increase in pain tolerance. Naloxone, on the other hand, is included to prevent the euphoric effects associated with opioid misuse, thereby mitigating the risk of dependency.

Dosage and Administration

  • Dosage: The typical dose is one tablet taken every 12 hours. Dosage may be adjusted based on the severity of pain and the patient’s response to treatment.
  • Administration: Tablets should be swallowed whole with a glass of water. Do not crush, chew, or dissolve the tablets to avoid tampering with the controlled-release mechanism.
  • Frequency: Administered twice daily, as prescribed by a healthcare provider.

Contraindications

Tilidin 50x 200/16mg should not be used in:

  • Patients with known hypersensitivity to Tilidine, Naloxone, or any of the excipients.
  • Individuals with severe respiratory depression or conditions with increased intracranial pressure.
  • Patients with acute alcoholism or concurrent use of other central nervous system depressants.

Warnings and Precautions

  • Respiratory Depression: Use with caution in patients with compromised respiratory function.
  • Dependency and Abuse Potential: Regular monitoring for signs of misuse, abuse, and addiction is essential.
  • Interactions: May interact with other medications, especially central nervous system depressants, MAO inhibitors, and certain antidepressants.
  • Pregnancy and Lactation: Use during pregnancy and breastfeeding is not recommended unless absolutely necessary.

Side Effects

Common side effects may include:

  • Nausea and vomiting
  • Dizziness and drowsiness
  • Constipation
  • Headache
  • Sweating

Serious side effects require immediate medical attention and include:

  • Respiratory depression
  • Severe allergic reactions
  • Confusion and hallucinations
  • Seizures

Storage Conditions

  • Store at room temperature (15-25°C) in a dry place.
  • Keep out of reach of children.
  • Protect from light and moisture.

Conclusion

Tilidin 50x 200/16mg by Hexal AG is a powerful analgesic designed to manage severe pain while minimizing the risk of opioid abuse. Its dual-component formulation makes it an effective and safer option for patients requiring long-term pain management under strict medical supervision. Always consult with a healthcare professional before starting or adjusting the dosage of this medication.

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