Introduction: Pfizer Viagra 100mg tablets are a widely recognized medication used to treat erectile dysfunction (ED) in men. Manufactured by Pfizer Inc., a renowned pharmaceutical company, these tablets contain sildenafil citrate as the active ingredient. Sildenafil citrate belongs to a class of medications known as phosphodiesterase type 5 (PDE5) inhibitors, which work by increasing blood flow to the penis during sexual stimulation. This helps men achieve and maintain a firm erection suitable for sexual activity.
Mechanism of Action: The mechanism of action of Pfizer Viagra 100mg revolves around its ability to inhibit the enzyme phosphodiesterase type 5 (PDE5). During sexual arousal, nitric oxide is released into the erectile tissue of the penis. Nitric oxide activates the enzyme guanylate cyclase, resulting in an increased production of cyclic guanosine monophosphate (cGMP). This cyclic nucleotide relaxes smooth muscles in blood vessels, allowing increased blood flow into the penis, which is essential for achieving an erection. Sildenafil citrate enhances this process by inhibiting PDE5, which degrades cGMP. By inhibiting PDE5, sildenafil citrate helps to maintain adequate levels of cGMP, promoting prolonged smooth muscle relaxation and sustained erection.
Indications and Usage: Pfizer Viagra 100mg tablets are indicated for the treatment of erectile dysfunction (ED) in adult men. Erectile dysfunction is defined as the consistent inability to achieve or maintain a penile erection sufficient for satisfactory sexual performance. This medication is effective only in the presence of sexual stimulation and does not increase sexual desire. It is important to note that Pfizer Viagra 100mg does not protect against sexually transmitted diseases (STDs) such as HIV, hepatitis B, gonorrhea, syphilis.
Dosage and Administration: The recommended dose of Pfizer Viagra 100mg is one tablet taken orally as needed, approximately 30 minutes to 1 hour before sexual activity. The onset of action may vary among individuals, but the effects typically last for about 4 to 5 hours. The tablet should be swallowed whole with a full glass of water. It can be taken with or without food, but fatty meals may delay the onset of action. The maximum recommended dosing frequency is once per day. Dosage adjustments may be necessary based on individual response and tolerability.
Contraindications: Pfizer Viagra 100mg tablets are contraindicated in patients with a known hypersensitivity to sildenafil citrate or any inactive ingredients in the formulation. Concomitant use with nitrate medications, such as nitroglycerin or isosorbide mononitrate, is contraindicated due to the potential for severe hypotension. Use of Pfizer Viagra 100mg is also contraindicated in patients who are taking guanylate cyclase stimulators, such as riociguat, as this combination can cause hypotension.
Adverse Reactions: Common adverse reactions associated with Pfizer Viagra 100mg include headache, flushing, dyspepsia, nasal congestion, dizziness, and visual disturbances (e.g., changes in color vision, blurred vision). These side effects are usually mild to moderate in nature and transient. Serious adverse reactions, such as priapism (prolonged erection exceeding 4 hours), sudden hearing loss, and cardiovascular events, have been reported rarely. Patients experiencing any serious adverse reactions should seek immediate medical attention.
Storage: Pfizer Viagra 100mg tablets should be stored at controlled room temperature (25°C / 77°F), away from excess heat and moisture. Keep the medication out of reach of children and pets. Do not use Pfizer Viagra 100mg tablets beyond the expiration date printed on the blister pack.
Conclusion: Pfizer Viagra 100mg tablets are a reliable and effective treatment option for men suffering from erectile dysfunction. With its proven ability to enhance erectile function by increasing blood flow to the penis, Pfizer Viagra 100mg helps restore confidence and sexual satisfaction. As with any medication, it is important to follow the prescribed dosage and instructions for use to achieve optimal results while minimizing the risk of adverse effects.
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