Buy DETRUSITOL SR 2mg (TOLTERODINE) Online

Overview

DETRUSITOL SR 2mg is a prescription medication designed for the treatment of overactive bladder with symptoms of urinary frequency, urgency, and incontinence. The active ingredient, Tolterodine, is an antimuscarinic agent that helps to relax the bladder muscles, thereby reducing bladder spasms.

Indications

• Overactive Bladder: DETRUSITOL SR is indicated for patients experiencing frequent urination, urgency to urinate, and urinary incontinence.

Mechanism of Action

Tolterodine works by blocking muscarinic receptors in the bladder. This inhibition reduces involuntary bladder contractions and increases bladder capacity, leading to a decrease in the urgency and frequency of urination.

Dosage and Administration

• Recommended Dose: The typical dosage for adults is one 2mg extended-release capsule taken once daily.
• Administration: Capsules should be taken whole with water, and can be taken with or without food. Do not crush or chew the capsules.

Contraindications

• Patients with urinary retention
• Gastric retention
• Uncontrolled narrow-angle glaucoma
• Known hypersensitivity to Tolterodine or any other ingredients in the formulation

Warnings and Precautions

• Use with caution in patients with significant bladder outflow obstruction, gastrointestinal obstructive disorders, or myasthenia gravis.
• Caution is advised in patients with impaired liver or kidney function.
• May cause drowsiness or blurred vision; patients should not drive or operate machinery until they know how the medication affects them.
• Regular monitoring may be necessary for patients on prolonged therapy.

Adverse Reactions

Common side effects include:

• Dry mouth
• Headache
• Constipation
• Dry eyes
• Dizziness
• Fatigue

Less common but serious side effects:

• Severe allergic reactions (rash, itching, swelling, severe dizziness, trouble breathing)
• Chest pain
• Confusion
• Hallucinations
• Severe abdominal pain

Drug Interactions

• Concomitant use with other antimuscarinic agents may increase the risk of anticholinergic side effects.
• CYP3A4 inhibitors (such as ketoconazole) may increase the plasma concentration of Tolterodine.
• Use caution when co-administering with medications that prolong the QT interval.

Storage

• Store at room temperature between 20°C to 25°C (68°F to 77°F).
• Keep out of reach of children.
• Protect from moisture and light.

Additional Information

• Prescription Status: DETRUSITOL SR is available by prescription only.
• Manufacturing Information: Manufactured by Pfizer, a leading global pharmaceutical company known for its commitment to quality and safety.

For any further information, consult your healthcare provider or the detailed product leaflet provided with the medication.