Chemical name: 1-(((3-(3,4-dihydro-5-methyl)-4-oxo-7-propylimidazo(5,1-f)-as-triazin-2-yl)-4-ethoxyphenyl)sulfonyl)-4-ethylpiperazine
Formula: C23H32N6O4S
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid
ZHEWITRA SOFT-20 (SUBLINGUAL)
Product Overview:
ZHEWITRA SOFT-20 is a pharmaceutical product manufactured by Sunrise Remedies, designed to address erectile dysfunction (ED) in men. Each package contains 10 soft tablets, each delivering 20 mg of Vardenafil HCL, a potent phosphodiesterase type 5 (PDE5) inhibitor. This medication aids in achieving and maintaining an erection sufficient for sexual intercourse by increasing blood flow to the penis in response to sexual stimulation.
Active Ingredient:
The active ingredient in ZHEWITRA SOFT-20 is Vardenafil Hydrochloride (HCL), a well-established treatment for ED. Vardenafil belongs to a class of drugs known as PDE5 inhibitors, which work by blocking the enzyme phosphodiesterase type 5. This action enhances the effects of nitric oxide, a natural chemical in the body that relaxes muscles and increases blood flow to the penis.
Mechanism of Action:
Upon ingestion, Vardenafil is rapidly absorbed into the bloodstream and acts to inhibit the PDE5 enzyme, which normally breaks down cyclic guanosine monophosphate (cGMP). By blocking this enzyme, ZHEWITRA SOFT-20 promotes increased levels of cGMP, leading to enhanced relaxation of the smooth muscles in the corpus cavernosum. This results in increased blood flow to the penis, facilitating an erection in response to sexual arousal.
Dosage and Administration:
The recommended starting dose for most men is 10 mg, taken orally approximately 60 minutes before sexual activity. However, for some patients, a 20 mg dose may be prescribed if the lower dose is insufficient. The maximum recommended frequency is one dose per day. ZHEWITRA SOFT-20 is designed to be taken as needed and should not be taken more than once within a 24-hour period.
The tablets are formulated to be soft and chewable, allowing for easy administration and quicker absorption compared to traditional hard tablets. This formulation ensures that the medication starts working faster, often within 30 to 60 minutes of ingestion, and provides a more convenient option for patients.
Indications:
ZHEWITRA SOFT-20 is indicated for the treatment of erectile dysfunction in adult men. Erectile dysfunction is characterized by the inability to achieve or maintain an erection adequate for satisfactory sexual performance. This condition can have various underlying causes, including psychological, physiological, or a combination of both. By enhancing blood flow to the penis, ZHEWITRA SOFT-20 addresses the physical aspects of ED, helping men regain their sexual confidence.
Side Effects:
Common side effects of ZHEWITRA SOFT-20 may include headaches, flushing, nasal congestion, indigestion, and dizziness. These effects are typically mild and transient. However, if any severe side effects occur, such as prolonged or painful erections (priapism), sudden vision loss, or allergic reactions, immediate medical attention should be sought. Patients with a history of cardiovascular issues, including recent stroke or heart attack, should consult with their healthcare provider before starting treatment.
Contraindications:
ZHEWITRA SOFT-20 should not be used in combination with nitrates or nitrate-containing medications, as this can lead to a dangerous drop in blood pressure. It is also contraindicated in patients who have a known hypersensitivity to Vardenafil or any other components of the tablet. Individuals with severe liver impairment or severe renal insufficiency should use this medication with caution and under strict medical supervision.
Interactions:
Drug interactions can occur with certain medications, including but not limited to, alpha-blockers, antihypertensives, and other PDE5 inhibitors. Patients should inform their healthcare provider of all medications and supplements they are currently taking to avoid potential interactions. Grapefruit juice and other substances that can affect liver enzyme activity may also alter the effectiveness of ZHEWITRA SOFT-20.
Storage:
ZHEWITRA SOFT-20 should be stored at room temperature, away from excess moisture and heat. The tablets should be kept out of reach of children and should not be used beyond the expiration date indicated on the packaging.
Conclusion:
ZHEWITRA SOFT-20, manufactured by Sunrise Remedies, offers an effective solution for men experiencing erectile dysfunction. With its chewable formulation and active ingredient Vardenafil HCL, this medication provides a convenient and reliable option for improving sexual performance and enhancing quality of life. As with all medications, it is important to use ZHEWITRA SOFT-20 under the guidance of a healthcare professional to ensure safe and effective treatment.
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