Chemical name: 1-(((3-(3,4-dihydro-5-methyl)-4-oxo-7-propylimidazo(5,1-f)-as-triazin-2-yl)-4-ethoxyphenyl)sulfonyl)-4-ethylpiperazine
Formula: C23H32N6O4S
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid
VILITRA-40
Overview
Vilitra-40 is a potent oral medication designed to treat erectile dysfunction (ED) in men. Each tablet contains 40 mg of Vardenafil, a selective phosphodiesterase type 5 (PDE5) inhibitor. Manufactured by Centurion Laboratories, Vilitra-40 is known for its reliability, effectiveness, and quick onset of action. It offers a solution for those who struggle with achieving or maintaining an erection sufficient for sexual activity, thereby enhancing the quality of life and sexual satisfaction for both the user and their partner.
Active Ingredient and Mechanism of Action
The active ingredient in Vilitra-40 is Vardenafil, a PDE5 inhibitor. PDE5 is an enzyme found in the smooth muscle of the penis that degrades cyclic guanosine monophosphate (cGMP), a molecule responsible for relaxing smooth muscles and increasing blood flow. Vardenafil inhibits the action of PDE5, leading to an increase in cGMP levels. This enhanced cGMP concentration facilitates the relaxation of smooth muscles and vasodilation within the corpus cavernosum, a sponge-like region in the penis that fills with blood during an erection. Consequently, this mechanism helps achieve and maintain a firm erection when combined with sexual stimulation.
Indications
Vilitra-40 is primarily indicated for the treatment of erectile dysfunction in adult men. It is suitable for individuals who experience difficulty achieving or maintaining an erection sufficient for satisfactory sexual performance. ED can result from various causes, including psychological factors, medical conditions such as diabetes or cardiovascular diseases, and certain medications. Vilitra-40 is effective across a wide range of ED causes and severities.
Dosage and Administration
Vilitra-40 comes in the form of oral tablets, each containing 40 mg of Vardenafil. The recommended starting dose for most men is one tablet taken orally, approximately 30 to 60 minutes before planned sexual activity. The medication can be taken with or without food; however, a high-fat meal may delay its onset of action.
It is essential to note that Vilitra-40 should not be taken more than once per day. The maximum recommended dosing frequency is once every 24 hours. Patients should not exceed the prescribed dose to avoid adverse effects and potential health risks.
Onset and Duration of Action
Vilitra-40 is known for its relatively rapid onset of action, typically within 30 to 60 minutes after ingestion. The effects of the medication can last for up to 4 to 5 hours, allowing for a sufficient window of opportunity for sexual activity. However, the duration can vary depending on individual factors, such as metabolism, age, and overall health.
Effectiveness
Clinical studies have demonstrated that Vilitra-40 is highly effective in treating erectile dysfunction, even in men with underlying health conditions such as diabetes and hypertension. It has been shown to improve erectile function, rigidity, and the ability to maintain an erection suitable for intercourse. Many users report significant improvements in sexual performance and satisfaction.
Side Effects
Like all medications, Vilitra-40 can cause side effects, although not everyone will experience them. Common side effects may include:
- Headache: This is one of the most frequently reported side effects and is usually mild to moderate in intensity.
- Flushing: A sensation of warmth or redness, particularly on the face and neck.
- Nasal Congestion: Some users may experience stuffiness or a runny nose.
- Indigestion: Mild gastrointestinal discomfort or upset stomach can occur.
- Dizziness: A feeling of lightheadedness, especially when getting up quickly from a sitting or lying position.
Less common but more serious side effects may include:
- Visual Disturbances: Changes in color vision or blurred vision.
- Hearing Loss: Sudden decrease or loss of hearing.
- Priapism: A prolonged and painful erection lasting more than 4 hours, which requires immediate medical attention.
- Cardiovascular Effects: Such as chest pain, palpitations, or an irregular heartbeat.
Patients experiencing any severe or persistent side effects should seek medical attention promptly.
Contraindications and Precautions
Vilitra-40 is contraindicated in individuals with the following conditions:
- Allergy to Vardenafil: Patients with known hypersensitivity to Vardenafil or any of the inactive ingredients in Vilitra-40 should not take this medication.
- Use of Nitrates: Concurrent use of nitrates (often prescribed for chest pain or heart conditions) and Vardenafil can lead to a dangerous drop in blood pressure.
- Severe Cardiovascular Disorders: Patients with recent history of heart attack, stroke, or severe hypotension should avoid using this medication without medical advice.
- Severe Liver or Kidney Disease: Impaired liver or kidney function can affect the metabolism and excretion of Vardenafil, necessitating dosage adjustments or alternative therapies.
Precautions should also be taken by individuals with anatomical deformation of the penis (such as Peyronie’s disease), a history of priapism, or those taking other medications that affect the QT interval.
Drug Interactions
Vilitra-40 can interact with various medications, potentially altering its effectiveness or increasing the risk of side effects. Notable drug interactions include:
- Nitrates: As mentioned, the combination of Vardenafil with nitrates can cause severe hypotension.
- Alpha-Blockers: Used for treating prostate enlargement or high blood pressure, these medications can increase the hypotensive effects of Vardenafil.
- CYP3A4 Inhibitors: Drugs such as ketoconazole, itraconazole, and certain antibiotics or antiviral medications can increase Vardenafil levels in the blood, necessitating dosage adjustments.
Patients should provide a comprehensive list of all medications they are taking, including over-the-counter drugs and supplements, to their healthcare provider before starting Vilitra-40.
Storage and Handling
Vilitra-40 should be stored at room temperature, away from moisture, heat, and direct sunlight. Keep the medication in its original packaging to protect it from light and moisture. It should be kept out of reach of children and pets to prevent accidental ingestion.
Conclusion
Vilitra-40 (Vardenafil Tablets 40mg) by Centurion Laboratories offers a reliable and effective treatment for erectile dysfunction in men. With its rapid onset, strong efficacy, and relatively long duration of action, it provides a practical solution for those seeking to improve their sexual health and overall quality of life. However, as with all medications, it should be used responsibly and under the guidance of a healthcare provider to ensure safety and effectiveness.
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