Sildenafil Citrate 100mg
Tadalafil 20mg
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid
SILDALIST
Sildalist combines the potency of two active ingredients, Sildenafil Citrate and Tadalafil, in a single tablet formulation, manufactured by Parex. This medication is designed to address erectile dysfunction (ED) effectively and offer prolonged efficacy for enhanced sexual performance and satisfaction.
Composition and Active Ingredients:
Each tablet of Sildalist contains:
- Sildenafil Citrate 100mg: Known for its role in inhibiting the enzyme phosphodiesterase type 5 (PDE5), Sildenafil Citrate promotes increased blood flow to the penile region during sexual stimulation. This mechanism supports achieving and maintaining firm erections necessary for satisfactory sexual intercourse.
- Tadalafil 20mg: This phosphodiesterase type 5 (PDE5) inhibitor enhances the effects of nitric oxide released during sexual stimulation, leading to relaxation of the smooth muscles in the penile arteries and facilitating blood flow. Tadalafil ensures prolonged erectile function up to 36 hours, allowing for greater flexibility and spontaneity in sexual activity.
Manufacturer and Brand Information:
Sildalist is manufactured by Parex, a reputable pharmaceutical company known for its commitment to quality and innovation in producing medications for various health conditions, including erectile dysfunction.
Indications and Usage:
Sildalist is indicated for the treatment of erectile dysfunction (ED) in adult males. It is suitable for men experiencing difficulty achieving or sustaining an erection sufficient for sexual intercourse. The dual-action formula of Sildalist ensures both rapid onset and prolonged duration of action, making it a preferred choice for many individuals seeking effective ED treatment.
Mechanism of Action:
- Sildenafil Citrate acts by inhibiting the enzyme PDE5, thereby promoting the accumulation of cyclic guanosine monophosphate (cGMP) in the smooth muscle cells of the penile arteries. This accumulation relaxes the muscles and increases blood flow to the penis, facilitating an erection.
- Tadalafil works similarly by inhibiting PDE5 and enhancing the effects of nitric oxide, resulting in smooth muscle relaxation and increased blood flow to the penile tissues. Its extended half-life ensures sustained efficacy over a longer period compared to other ED medications.
Administration and Dosage:
- Sildalist tablets are typically taken orally with water, approximately 30 minutes to 1 hour before anticipated sexual activity.
- The recommended initial dose is one tablet (Sildenafil Citrate 100mg + Tadalafil 20mg) per day.
- Dosage adjustment may be necessary based on individual response and tolerability. It is essential to follow the prescribing physician’s instructions regarding dosage and administration.
Contraindications:
- Sildalist is contraindicated in individuals with known hypersensitivity to Sildenafil Citrate, Tadalafil, or any inactive ingredients present in the formulation.
- It should not be used concomitantly with nitrate-based medications or recreational drugs (e.g., amyl nitrite) as serious interactions leading to severe hypotension can occur.
Adverse Effects:
Common side effects associated with Sildalist may include headache, facial flushing, indigestion, nasal congestion, and dizziness. These effects are generally mild and transient, resolving on their own without medical intervention.
Precautions and Warnings:
- Use caution when prescribing Sildalist to patients with pre-existing cardiovascular conditions, liver or kidney impairment, or anatomical deformation of the penis.
- Avoid excessive alcohol consumption while taking Sildalist, as it may increase the likelihood of adverse effects.
- Individuals with a history of priapism (prolonged erection lasting more than 4 hours) should seek immediate medical attention.
Storage:
- Store Sildalist tablets in a cool, dry place away from direct sunlight and moisture.
- Keep out of reach of children and pets.
Conclusion:
Sildalist by Parex offers a dual-action approach to treating erectile dysfunction with its combination of Sildenafil Citrate and Tadalafil. This innovative formulation ensures both rapid onset and prolonged duration of action, providing men with greater confidence and satisfaction in their sexual relationships. As with any prescription medication, it is crucial to consult a healthcare provider for personalized advice and optimal use.
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