Chemical name: 4-[(4-cyanophenyl)-(1,2,4-triazol-1-yl)methyl]benzonitrile;
Formula: C17H11N5
Femara is a brand name for the medication letrozole. It belongs to a class of drugs known as aromatase inhibitors and is commonly used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. Below is a general description of Femara:
Composition and Mechanism of Action:
- Active Ingredient: Letrozole is the active ingredient in Femara.
- Aromatase Inhibitor: Femara is classified as an aromatase inhibitor, which means it inhibits the enzyme aromatase, responsible for converting androgens into estrogen. By blocking this process, Femara reduces estrogen levels in the body.
Indications:
- Breast Cancer Treatment: Femara is primarily used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It is often prescribed as part of adjuvant therapy or extended adjuvant therapy following surgery or other treatments.
Dosage and Administration:
- The dosage of Femara may vary depending on the specific type and stage of breast cancer being treated. It is usually taken orally in the form of a tablet.
Monitoring:
- Regular monitoring, including blood tests to assess hormone levels and imaging studies, may be recommended during the course of breast cancer treatment with Femara.
Side Effects:
- Common side effects of Femara may include hot flashes, joint pain, fatigue, and increased sweating. Serious side effects, although rare, may include bone density loss and an increased risk of fractures.
Contraindications:
- Femara is generally contraindicated in premenopausal women, pregnant women, and women with a history of hypersensitivity to letrozole.
Precautions:
- Femara should be used with caution in individuals with a history of osteoporosis, as it may contribute to bone density loss. Adequate calcium and vitamin D intake are often recommended.
Patient Counseling:
- Patients prescribed Femara should be educated about its proper use, potential side effects, and the importance of regular follow-up appointments with a healthcare provider.
Pregnancy and Breastfeeding:
- Femara is not intended for use in premenopausal women, and it may cause harm to a developing fetus. It is not recommended during pregnancy or breastfeeding.
It’s essential to note that the information provided here is a general overview, and specific details regarding the use of Femara should be discussed with a healthcare professional. The medication should be used under the guidance and supervision of a qualified healthcare provider based on the individual’s medical history and specific health needs.
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