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Buy Lucaftor (lumacaftor/ivacaftor) Online

DISEASE INDICATIONS: Cystic Fibrosis

MANUFACTURER: Gador SA

USAGE: Oral

MEDICINE APPROVED BY:

ANMAT (ARG)

 

Lucaftor is not a standalone medication but a combination therapy that consists of two active ingredients: lumacaftor and ivacaftor. This combination medication is used for the treatment of a specific genetic disorder known as cystic fibrosis (CF). It is designed to address the underlying cause of CF in individuals who have a specific mutation in the CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) gene.

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Lucaftor is not a standalone medication but a combination therapy that consists of two active ingredients: lumacaftor and ivacaftor. This combination medication is used for the treatment of a specific genetic disorder known as cystic fibrosis (CF). It is designed to address the underlying cause of CF in individuals who have a specific mutation in the CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) gene.

Here is a detailed description of Lucaftor, which is essentially a combination of lumacaftor and ivacaftor:

Name: Lucaftor (Combination of Lumacaftor and Ivacaftor)

Active Ingredients:

  1. Lumacaftor: Lumacaftor is a CFTR corrector medication. It works by helping the defective CFTR protein in the cells of the respiratory system fold properly and move to the cell surface. This allows the CFTR protein to function more effectively in regulating the flow of salt and fluids in and out of the cells, which helps improve mucus clearance and reduces the buildup of thick, sticky mucus in the airways.
  2. Ivacaftor: Ivacaftor is a CFTR potentiator medication. It works by enhancing the function of the CFTR protein that has reached the cell surface. This helps increase chloride ion transport, further improving the hydration of the airway surface and making mucus less thick and easier to clear.

Indications: Lucaftor (lumacaftor/ivacaftor) is specifically indicated for the treatment of cystic fibrosis in patients who are homozygous for the F508del mutation in the CFTR gene. This mutation is one of the most common causes of CF, and Lucaftor is designed to address the underlying genetic defect in individuals with this mutation.

Dosage Forms: Lucaftor is typically available in the form of oral tablets or granules, which are taken by mouth.

Usage: The dosing and administration of Lucaftor are determined by a healthcare provider and are based on the patient’s age and weight. It is generally taken twice daily with fat-containing food to optimize absorption.

Benefits: Lucaftor offers the potential to improve lung function, reduce respiratory symptoms, and enhance the overall quality of life for individuals with cystic fibrosis who have the F508del mutation. It is not a cure for CF but can help manage the underlying genetic defect.

Precautions: Before starting Lucaftor, patients should undergo genetic testing to determine if they have the specific F508del mutation that this medication is designed to treat. It is important to use Lucaftor as prescribed by a healthcare provider and to be aware of potential side effects and drug interactions.

Side Effects: Common side effects of Lucaftor may include respiratory symptoms like shortness of breath, cough, and chest tightness. Other possible side effects can include abdominal pain, diarrhea, and elevated liver enzymes. Patients should discuss any side effects or concerns with their healthcare provider.

In summary, Lucaftor (lumacaftor/ivacaftor) is a combination medication used for the treatment of cystic fibrosis in individuals with the F508del mutation. It addresses the underlying genetic defect to improve lung function and reduce respiratory symptoms associated with CF. Patients should use it as directed by their healthcare provider and be aware of potential side effects and precautions associated with its use.

Package

200/125 mg

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