Zegalogue (dasiglucagon) is a prescription medication used to treat severe hypoglycemia (very low blood sugar) in adults and children with diabetes aged 6 years and older.
How does Zegalogue work?
Zegalogue is a glucagon receptor agonist. Glucagon is a hormone that helps to raise blood sugar levels. Zegalogue works by stimulating glucagon receptors in the liver, which causes the liver to release glucose into the bloodstream.
How is Zegalogue used?
Zegalogue is given as a single injection under the skin. The recommended dose for adults and children aged 6 years and older is 0.6 mg. If there is no response after 15 minutes, an additional 0.6 mg dose may be given.
What are the side effects of Zegalogue?
The most common side effects of Zegalogue are:
- Nausea
- Vomiting
- Headache
- Diarrhea
- Injection site pain
Zegalogue can also cause more serious side effects, such as:
- Allergic reactions
- Increased heart rate
- Increased blood pressure
- Decreased blood sugar levels (too low)
Who should not take Zegalogue?
Zegalogue should not be taken by people who are allergic to dasiglucagon or any of the other ingredients in Zegalogue. It should also not be taken by people with:
- Pheochromocytoma (a rare tumor of the adrenal gland)
- Severe insulinoma (a tumor of the pancreas that produces too much insulin)
Important safety information
It is important to tell your doctor about all of the medications you are taking before starting Zegalogue. Zegalogue can interact with other drugs, such as beta-blockers and calcium channel blockers.
Zegalogue should be used with caution in people with heart disease, high blood pressure, and kidney disease.
Zegalogue can cause serious side effects, such as allergic reactions and decreased blood sugar levels. It is important to monitor your blood sugar levels closely while taking Zegalogue.
If you are considering taking Zegalogue, talk to your doctor about the risks and benefits of the medication.
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