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Buy Palynziq (pegvaliase-pqpz) Online

DISEASE INDICATIONS: phenylketonuria (PKU)

MANUFACTURER: BioMarin Pharmaceutical Inc.

USAGE: Subcutaneous

MEDICINE APPROVED BY:

European Medical Agency (EMA)

Food and Drug Administration (FDA)

Palynziq (pegvaliase-pqpz) is a prescription medication used to lower blood levels of phenylalanine (Phe) in adults with phenylketonuria (PKU) who have uncontrolled blood Phe levels above 600 micromol/L (10 mg/dL) on their current treatment. PKU is a rare genetic disorder that prevents the body from breaking down the amino acid phenylalanine. Phenylalanine can build up in the blood and cause serious health problems, such as intellectual disability, seizures, and behavioral problems.

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Palynziq (pegvaliase-pqpz) is a prescription medication used to lower blood levels of phenylalanine (Phe) in adults with phenylketonuria (PKU) who have uncontrolled blood Phe levels above 600 micromol/L (10 mg/dL) on their current treatment. PKU is a rare genetic disorder that prevents the body from breaking down the amino acid phenylalanine. Phenylalanine can build up in the blood and cause serious health problems, such as intellectual disability, seizures, and behavioral problems.

Palynziq is an enzyme replacement therapy (ERT) drug. It works by replacing the missing or defective phenylalanine hydroxylase (PAH) enzyme, which is responsible for breaking down phenylalanine. Palynziq is given as a once-daily subcutaneous injection.

How effective is Palynziq?

In clinical studies, Palynziq was shown to be effective in lowering blood Phe levels in patients with PKU. In one study, Palynziq reduced blood Phe levels by a median of 60% after 12 weeks of treatment.

What are the side effects of Palynziq?

The most common side effects of Palynziq are:

  • Injection site reactions
  • Headache
  • Fatigue
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Abdominal pain
  • Back pain
  • Muscle pain
  • Upper respiratory tract infection

Palynziq can also cause more serious side effects, such as:

  • Allergic reactions, including anaphylaxis (a life-threatening allergic reaction)
  • Decreased liver function
  • Decreased kidney function
  • Infusion-related reactions
  • Increased risk of infection

Who should not take Palynziq?

Palynziq should not be taken by people who are allergic to pegvaliase-pqpz or any of the other ingredients in Palynziq.

Important safety information

It is important to tell your doctor about all of the medications you are taking before starting Palynziq. Palynziq can interact with other drugs, such as certain antibiotics and anticonvulsants.

Palynziq should be used with caution in people with liver disease or kidney disease.

Palynziq can cause serious side effects, such as allergic reactions and decreased liver function. It is important to monitor your liver function regularly while taking Palynziq.

If you are considering taking Palynziq, talk to your doctor about the risks and benefits of the medication.

Package

1 single-dose prefilled syringe of 2.5 mg/0.5 mL, 1 single-dose prefilled syringe of 10 mg/0.5 mL, 1 single-dose prefilled syringe of 20 mg/1 mL, 10 single-dose prefilled syringes of 20 mg/1 mL

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