Buy Orladeyo (berotralstat) Online

Orladeyo is a prescription medication that contains berotralstat, used to prevent attacks of hereditary angioedema (HAE). It is a subcutaneous injection that can be self-administered by patients or by a healthcare provider.

Uses:

Orladeyo is used for the prevention of attacks of hereditary angioedema (HAE) in adults and children 12 years and older, by reducing the frequency of attacks.

Storage Conditions:

Orladeyo should be stored in the refrigerator between 36°F and 46°F (2°C and 8°C). Before use, the medication should be allowed to sit at room temperature for 30 minutes.

Mechanism of Action:

Orladeyo works by inhibiting kallikrein, an enzyme involved in the production of bradykinin. Bradykinin is a molecule that causes inflammation and swelling, leading to the symptoms of HAE. By inhibiting kallikrein, Orladeyo reduces the production of bradykinin, preventing HAE attacks.

HOW TO USE:

Orladeyo is a subcutaneous injection that can be self-administered by patients or by a healthcare provider. The medication should be taken once daily at the same time each day, with or without food. The initial dose is 110 mg, followed by a maintenance dose of 150 mg or 110 mg based on tolerability. Patients should follow the instructions on the prescription label and use the medication exactly as directed by their healthcare provider.

Important Safety Information:

• Orladeyo may cause anaphylaxis, a severe and potentially life-threatening allergic reaction. Patients should seek emergency medical attention immediately if they experience symptoms of anaphylaxis such as difficulty breathing, swelling of the face, lips, tongue, or throat, or severe itching or skin rash.
• The medication may also cause hypersensitivity reactions, including rash, itching, and hives. Patients should notify their healthcare provider if they experience any unusual symptoms while taking Orladeyo.
• Orladeyo may interact with other medications, and patients should inform their healthcare provider of all medications they are taking, including supplements and herbal remedies.

Indications:

• Orladeyo is indicated for the prevention of attacks of hereditary angioedema (HAE) in adults and children 12 years and older.

Precautions:

• Patients with a history of hypersensitivity to berotralstat or who have experienced an allergic reaction to the medication should not take Orladeyo.
• The medication should be used with caution in patients with liver or kidney disease.

Interactions:

• Orladeyo may interact with other medications such as P-gp inhibitors and inducers.
• Patients should inform their healthcare provider of all medications they are taking, including supplements and herbal remedies, before starting treatment with Orladeyo.

Contraindications:

• Orladeyo is contraindicated in patients with a history of hypersensitivity to berotralstat or any of its components.

Overdose:

In case of an overdose, patients should seek emergency medical attention immediately.

Side Effects:

The most common side effects of Orladeyo include injection site reactions, such as redness, swelling, and itching. Other possible side effects may include abdominal pain, nausea, vomiting, and headache. Patients should notify their healthcare provider if they experience any unusual symptoms while taking Orladeyo.

In conclusion, Orladeyo is a subcutaneous injection used for the prevention of attacks of hereditary angioedema (HAE) in adults and children. It works by inhibiting kallikrein, an enzyme involved in the production of bradykinin, preventing HAE attacks. Patients should follow the instructions on the prescription label and use the medication exactly as directed by their healthcare provider. Orladeyo may cause anaphylaxis or hypersensitivity reactions, and patients with a history of hypersensitivity or allergies to berotralstat or its components should not take the medication. The medication should be stored in the refrigerator, and patients should avoid using it if it has been left out of the refrigerator for more than 24 hours.